Understanding Programming in Highly Reducing Iterative Fungal Polyketide Synthases - a Structural and Mechanistic Approach

Simpson, Thomas J (Principal Investigator)

School of Chemistry

Status	Finished
Effective start/end date	1/07/11 → 1/01/15

Research Groups and Themes

BCS and TECS CDTs
BrisSynBio
Bristol BioDesign Institute
Organic & Biological

11 Article (Academic Journal)

Structural and Synthetic Studies on Maleic Anhydride and Related Diacid Natural Products.
Heard, D. M., Cox, R., Simpson, T. J. & Willis, C. L., 18 Oct 2019, (Accepted/In press) In: Tetrahedron.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
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6 Citations (Scopus)

949 Downloads (Pure)
In vitro kinetic study of the squalestatin tetraketide synthase dehydratase reveals the stereochemical course of a fungal highly reducing polyketide synthase
Liddle, E., Scott, A., Han, L. C., Ivison, D., Simpson, T. J., Willis, C. L. & Cox, R. J., 4 Feb 2017, In: Chemical Communications. 53, 10, p. 1727-1730 4 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
File
18 Citations (Scopus)

409 Downloads (Pure)
Recognition of extended linear and cyclised polyketide mimics by a Type II acyl carrier protein
Dong, X., Bailey, C., Williams, C., Crosby, J., Simpson, T., Willis, C. & Crump, M., 1 Mar 2016, In: Chemical Science. 7, 3, p. 1779-1785 7 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access
File
11 Citations (Scopus)

403 Downloads (Pure)