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α-arylation of cyclic amines by aryl transfer in lithiated ureas

  • Renaud Bach
  • , Jonathan Clayden*
  • , Ulrich Hennecke
  • *Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

35 Citations (Scopus)

Abstract

Treatment with base of N′-aryl urea derivatives of hetero-or carbocyclic amines with benzylic nitrogen atoms promotes rearrangement with transfer of the aryl ring from N to C, giving rise to α-arylated products.

Original languageEnglish
Pages (from-to)421-424
Number of pages4
JournalSynlett
Issue number3
Early online date21 Jan 2009
DOIs
Publication statusPublished - Feb 2009

Research Groups and Themes

  • Organic & Biological

Keywords

  • Amines
  • Arylation
  • Heterocycles
  • Lithiation
  • Ureas

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