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Abstract
Two different strategies for the synthesis of functionalised γ-lactones from δ-lactones are described and used in a convergent synthesis of (+)-mupirocin H. The total synthesis is versatile and may be readily adapted for the preparation of further truncated metabolites from Pseudomonas fluorescens.
Original language | English |
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Pages (from-to) | 2639-41 |
Number of pages | 3 |
Journal | Chemical Communications |
Volume | 48 |
Issue number | 20 |
DOIs | |
Publication status | Published - 2012 |
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Dive into the research topics of 'γ-Lactones from δ-lactones: total synthesis of the biosynthetic derailment product mupirocin H'. Together they form a unique fingerprint.Projects
- 1 Finished
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CHEMICAL ANALYSIS OF THE MUPIROCIN GENE CLUSTER FROM PSEUDOMONAS FLUORESCENS
Simpson, T. J.
1/10/04 → 1/01/08
Project: Research