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Two different strategies for the synthesis of functionalised γ-lactones from δ-lactones are described and used in a convergent synthesis of (+)-mupirocin H. The total synthesis is versatile and may be readily adapted for the preparation of further truncated metabolites from Pseudomonas fluorescens.
FingerprintDive into the research topics of 'γ-Lactones from δ-lactones: total synthesis of the biosynthetic derailment product mupirocin H'. Together they form a unique fingerprint.
- 1 Finished
Simpson, T. J.
1/10/04 → 1/01/08