10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Alison Halliday, Michael Harrison, Elizabeth Hayter, Xiangling Kong, Averil Mansfield, Joanna Marro, Hongchao Pan, Richard Peto, John Potter, Kazem Rahimi, Angela Rau, Steven Robertson, Jonathan Streifler, Dafydd Thomas, Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group, Frank C T Smith

Research output: Contribution to journalArticle (Academic Journal)peer-review

522 Citations (Scopus)

Abstract

If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.
Original languageEnglish
Pages (from-to)1074-84
Number of pages11
JournalLancet
Volume376
Issue number9746
DOIs
Publication statusPublished - 25 Sep 2010

Bibliographical note

Copyright © 2010 Elsevier Ltd. All rights reserved.

Keywords

  • Aged
  • Aged, 80 and over
  • Carotid Stenosis
  • Endarterectomy, Carotid
  • Female
  • Humans
  • Incidence
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Primary Prevention
  • Stroke
  • Time Factors
  • Treatment Outcome

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