10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Alison Halliday; Michael Harrison; Elizabeth Hayter; Xiangling Kong; Averil Mansfield; Joanna Marro; Hongchao Pan; Richard Peto; John Potter; Kazem Rahimi; Angela Rau; Steven Robertson; Jonathan Streifler; Dafydd Thomas; Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group; Frank C T Smith

doi:10.1016/S0140-6736(10)61197-X

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Alison Halliday, Michael Harrison, Elizabeth Hayter, Xiangling Kong, Averil Mansfield, Joanna Marro, Hongchao Pan, Richard Peto, John Potter, Kazem Rahimi, Angela Rau, Steven Robertson, Jonathan Streifler, Dafydd Thomas, Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group, Frank C T Smith

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

794 Citations (Scopus)

Abstract

If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.

Original language	English
Pages (from-to)	1074-84
Number of pages	11
Journal	Lancet
Volume	376
Issue number	9746
DOIs	https://doi.org/10.1016/S0140-6736(10)61197-X
Publication status	Published - 25 Sept 2010

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Keywords

Aged
Aged, 80 and over
Carotid Stenosis
Endarterectomy, Carotid
Female
Humans
Incidence
Kaplan-Meier Estimate
Male
Middle Aged
Primary Prevention
Stroke
Time Factors
Treatment Outcome

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Halliday, A., Harrison, M., Hayter, E., Kong, X., Mansfield, A., Marro, J., Pan, H., Peto, R., Potter, J., Rahimi, K., Rau, A., Robertson, S., Streifler, J., Thomas, D., Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group, & Smith, F. C. T. (2010). 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial. Lancet, 376(9746), 1074-84. https://doi.org/10.1016/S0140-6736(10)61197-X

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title = "10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial",

abstract = "If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.",

keywords = "Aged, Aged, 80 and over, Carotid Stenosis, Endarterectomy, Carotid, Female, Humans, Incidence, Kaplan-Meier Estimate, Male, Middle Aged, Primary Prevention, Stroke, Time Factors, Treatment Outcome",

author = "Alison Halliday and Michael Harrison and Elizabeth Hayter and Xiangling Kong and Averil Mansfield and Joanna Marro and Hongchao Pan and Richard Peto and John Potter and Kazem Rahimi and Angela Rau and Steven Robertson and Jonathan Streifler and Dafydd Thomas and {Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group} and Smith, {Frank C T}",

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month = sep,

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doi = "10.1016/S0140-6736(10)61197-X",

language = "English",

volume = "376",

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Halliday, A, Harrison, M, Hayter, E, Kong, X, Mansfield, A, Marro, J, Pan, H, Peto, R, Potter, J, Rahimi, K, Rau, A, Robertson, S, Streifler, J, Thomas, D, Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group & Smith, FCT 2010, '10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial', Lancet, vol. 376, no. 9746, pp. 1074-84. https://doi.org/10.1016/S0140-6736(10)61197-X

TY - JOUR

T1 - 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1)

T2 - a multicentre randomised trial

AU - Halliday, Alison

AU - Harrison, Michael

AU - Hayter, Elizabeth

AU - Kong, Xiangling

AU - Mansfield, Averil

AU - Marro, Joanna

AU - Pan, Hongchao

AU - Peto, Richard

AU - Potter, John

AU - Rahimi, Kazem

AU - Rau, Angela

AU - Robertson, Steven

AU - Streifler, Jonathan

AU - Thomas, Dafydd

AU - Asymptomatic Carotid Surgery Trial (ACST) Collaborative Group

AU - Smith, Frank C T

PY - 2010/9/25

Y1 - 2010/9/25

N2 - If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.

AB - If carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.

KW - Aged

KW - Aged, 80 and over

KW - Carotid Stenosis

KW - Endarterectomy, Carotid

KW - Female

KW - Humans

KW - Incidence

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Primary Prevention

KW - Stroke

KW - Time Factors

KW - Treatment Outcome

U2 - 10.1016/S0140-6736(10)61197-X

DO - 10.1016/S0140-6736(10)61197-X

M3 - Article (Academic Journal)

C2 - 20870099

SN - 0140-6736

VL - 376

SP - 1074

EP - 1084

JO - Lancet

JF - Lancet

IS - 9746

ER -

10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial

Abstract

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Keywords

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