1H magnetic resonance spectroscopy metabolites as biomarkers for cell cycle arrest and cell death in rat glioma cells

Ladan Mirbahai, Martin Wilson, Christopher S Shaw, Carmel McConville, Roger D G Malcomson, Julian L Griffin, Risto A Kauppinen, Andrew C Peet

Research output: Contribution to journalArticle (Academic Journal)peer-review

30 Citations (Scopus)

Abstract

Improved non-invasive imaging biomarkers of treatment response contribute to optimising cancer management and metabolites detected by proton magnetic resonance spectroscopy ((1)H MRS) show promise in this area. Understanding (1)H MRS changes occurring in cells during cell stress and cell death in vitro should aid the selection of pertinent biomarkers for clinical use.
Original languageEnglish
Pages (from-to)990-1001
Number of pages12
JournalInternational Journal of Biochemistry and Cell Biology
Volume43
Issue number7
DOIs
Publication statusPublished - 2011

Structured keywords

  • Brain and Behaviour

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