6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children

JC Baranowski, T Baranowski, A Beltran, KB Watson, RP Jago, M Callie, M Missaghian, BJ Tepper

    Research output: Contribution to journalArticle (Academic Journal)

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    Abstract

    Objective To examine the relationship of 6-n-propylthiouracil (PROP) sensitivity to BMI while statistically controlling for demographic characteristics in two age groups of children: 9–10 years and 17–18 years (n 1551). Design Cross-sectional design with a multi-ethnic (White, African-American, Hispanic, Other) sample of 813 children aged 9–10 years and 738 children aged 17–18 years. Children were recruited from local elementary and high schools with at least 30 % minority ethnic enrolment. Children’s height, weight and waist circumference were measured along with their PROP taster status. PROP was measured using two paper discs, one impregnated with NaCl (1·0 mol/l) and the other with PROP solution (0·50 mmol/l). Results A significant PROP sensitivity by socio-economic status (SES) interaction term (P = 0·010) was detected wherein supertasters had the largest BMI percentile and Z-score, but only among the group with highest SES. Conclusions The results suggest that other factors overwhelmed the influence of PROP sensitivity on adiposity in lower-SES groups. The percentage of variance accounted for by the interaction term was about 1 %. Thus, PROP supertasters had the largest BMI percentile and Z-score, but only among the highest-SES group.
    Translated title of the contribution6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children
    Original languageEnglish
    Pages (from-to)1587 - 1592
    Number of pages6
    JournalPublic Health Nutrition
    Volume13 (10)
    DOIs
    Publication statusPublished - Oct 2010

    Bibliographical note

    Publisher: Cambridge University Press

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  • Cite this

    Baranowski, JC., Baranowski, T., Beltran, A., Watson, KB., Jago, RP., Callie, M., Missaghian, M., & Tepper, BJ. (2010). 6-n-Propylthiouracil sensitivity and obesity status among ethnically diverse children. Public Health Nutrition, 13 (10), 1587 - 1592. https://doi.org/10.1017/S1368980009993004