Abstract
Central pontine myelinolysis (CPM) is a neurological demyelinating disease of the pons. Although usually associated with rapid correction of hyponatremia, CPM may occur despite normonatremia, is often associated with chronic alcoholism and may be asymptomatic. Histological confirmation of asymptomatic CPM is rare. We describe an unusual post-mortem case of extensive but asymptomatic CPM in a chronic alcoholic patient with normonatremia. The affected part of the pons contained thinly myelinated axons with appearances supporting remyelination. We suggest that remyelination may account for the subclinical nature of this patient's CPM.
| Original language | English |
|---|---|
| Number of pages | 3 |
| Journal | Forensic Science, Medicine, and Pathology |
| Early online date | 25 Nov 2017 |
| DOIs | |
| Publication status | E-pub ahead of print - 25 Nov 2017 |
Research Groups and Themes
- Cerebrovascular and Dementia Research Group
Keywords
- Alcohol
- Asymptomatic
- Central pontine myelinolysis
- Post-mortem
- Remyelination
Access to Document
- Full-text PDF (final published version)
This is the final published version of the article (version of record). It first appeared online via SPRINGER at https://link.springer.com/article/10.1007%2Fs12024-017-9933-y#copyrightInformation. Please refer to any applicable terms of use of the publisher.