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A Comparison of the Outcomes of Simultaneous Bilateral and Unilateral Mobile-Bearing Unicompartmental Knee Arthroplasties: An Analysis of Data from the National Joint Registry of England, Northern Ireland and Isle of Man

Hasan Raza Mohammad*, Andrew Judge, David W Murray

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

Background
Unicompartmental knee arthroplasty (UKA) is an effective treatment for unicompartmental end-stage knee arthritis. Simultaneous bilateral UKAs for patients with bilateral knee arthritis can reduce costs, number of anesthetics, and overall rehabilitation time. It is unknown how the long-term outcomes of unilateral and simultaneous bilateral UKAs compare.

Methods
In total, 1,939 unilateral and 1,939 simultaneous bilateral medial mobile-bearing UKAs (n = 3,878) from the National Joint Registry were propensity score matched. Kaplan-Meier and Cox regression were used to compare implant survival, revision indications, and mortality.

Results
The 10-year implant survival in the simultaneous bilateral group was 92% (95% confidence interval [CI] 90-94) and in the unilateral group was 90% (95% CI 88-92). The simultaneous bilateral group had a lower revision risk (hazard ratio [HR] 0.73, p = 0.01). Revisions for pain were lower in the bilateral group (0.5% vs. 1.2%, p = 0.01). There were no differences in patient mortality. Subgroup analyses found similar trends in 10-year implant survival and revision risk with both cementless (simultaneous bilateral 98% CI 95-99; unilateral 95% CI 91-98; HR 0.66, p = 0.27) and cemented fixation (simultaneous bilateral 91% CI 89-93; unilateral 90% CI 88%-92%; HR 0.85, p = 0.28).

Conclusions
Simultaneous bilateral UKAs had better 10-year implant survival and similar mortality to compared with single-unilateral UKAs. For patients with severe symptomatic bilateral unicompartmental knee osteoarthritis, simultaneous bilateral UKAs could be considered to be a safe and effective procedure, particularly as only one operation and postoperative recovery is required.

Level of Evidence
Level IV. See Instructions for Authors for a complete description of levels of evidence.
Original languageEnglish
Article numbere25.00292
Pages (from-to)e25.00292
Number of pages8
JournalJBJS Open Access
Volume11
Issue number1
DOIs
Publication statusPublished - 3 Feb 2026

Bibliographical note

Publisher Copyright:
© 2026 The Authors. Published by The Journal of Bone and Joint Surgery, Incorporated. All rights reserved.

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