| Original language | English |
|---|---|
| Article number | 110685 |
| Journal | Cell Reports |
| Volume | 39 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 2022 |
Bibliographical note
Funding Information:We thank the Dana-Farber Cancer Institute (DFCI) Flow Cytometry Core and Mass Cytometry Core, John Daley II, Susan Lazo, Nicole Paul, Eric Haas, and Cory Williams for assistance with HTS FACS and CyTOF. We are grateful to the Harvard Medical School Single Cell Core: Mandovi Chaterjee, Sarah Boswell, and Alex Ratner for InDrops service, as well as Zach Herbert, Maura Berkeley, and Andrew Caruso of the DFCI Molecular Biology and Core Facilities (MBCF) for assisting us in scRNA-seq. We also thank Shannan Ho-Shui and Michael Steinbaugh of the Harvard Chan Bioinformatics Core, Harvard School of Public Health; Ian Taylor, Joel Connors, and Miguel Velasquez of FlowJo; and LLC/BD Biosciences for the data analytics support. E.A. is supported by the National Institutes of Health (NIH) grants R01HL136431, R01HL141917, and R01HL147095. M.A. is supported by NIH grants R01HL107550 and R01HL126901 and by Kowa Company, Nagoya, Japan. J.L.D. and E.A. conceived the project. J.L.D. and P.V. initiated the project. J.L.D. and Y.I. designed, performed, analyzed, and interpreted the data for the majority of the experiments. J.L.D. Y.I. S.G. J.T.M. A.H. L.H.L. and B.P. contributed analytic tools, analyzed data, and performed data visualization. J.L.D. Y.I. S.G. J.Y.L. S.C. J.S.-N. F.B.-L. P.V. E.G. H.S. S.A.S. J.W. and H.H. performed the experiments. J.L.D. and Y.I. drafted the original manuscript. S.A.S. M.B. and J.Y.L. contributed to the original manuscript drafting. S.C.B. provided the aortic valve specimens. J.L.D. E.A. M.B. and S.A.S. reviewed and edited the manuscript. J.L.D. revised the manuscript. J.L.D. J.T.M. S.C. and F.B.-L. performed experiments for the revision. E.A. supervised the project and provided funds and resources. M.A. is also supported by grants from Kowa Company, Ltd. Nagoya, Japan. One or more of the authors of this paper self-identifies as an underrepresented ethnic minority in science. While citing references scientifically relevant for this work, we also actively worked to promote gender balance in our reference list.
Funding Information:
We thank the Dana-Farber Cancer Institute (DFCI) Flow Cytometry Core and Mass Cytometry Core, John Daley II, Susan Lazo, Nicole Paul, Eric Haas, and Cory Williams for assistance with HTS FACS and CyTOF. We are grateful to the Harvard Medical School Single Cell Core: Mandovi Chaterjee, Sarah Boswell, and Alex Ratner for InDrops service, as well as Zach Herbert, Maura Berkeley, and Andrew Caruso of the DFCI Molecular Biology and Core Facilities (MBCF) for assisting us in scRNA-seq. We also thank Shannan Ho-Shui and Michael Steinbaugh of the Harvard Chan Bioinformatics Core, Harvard School of Public Health; Ian Taylor, Joel Connors, and Miguel Velasquez of FlowJo; and LLC/BD Biosciences for the data analytics support. E.A. is supported by the National Institutes of Health (NIH) grants R01HL136431 , R01HL141917 , and R01HL147095 . M.A. is supported by NIH grants R01HL107550 and R01HL126901 and by Kowa Company, Nagoya, Japan.
Funding Information:
M.A. is also supported by grants from Kowa Company, Ltd., Nagoya, Japan.
Publisher Copyright:
© 2022 The Authors
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