Methods: 938 overweight/obese adults completed baseline examinations and underwent an 8-week LCD, providing 3.3-4.2 MJ/day to replace all meals. Anthropometric measurements and body composition were assessed at baseline and post-LCD.
Results: 773 (82.4%) adults (mean age, 43.1 y) completed the LCD successfully. The highest drop-out was observed in the Southern (24.9%) and the lowest in the Northern (13.3%) European cities. Overall, the LCD induced favorable changes in all outcomes, including an approximate 11.0% reduction in body weight and body fat percentage. Changes in outcomes differed significantly between regions, with the North- and Central-European cities generally achieving higher percentage reductions in most anthropometric measurements assessed. Nonetheless, participants in Southern Europe reduced their body fat percentage significantly more than participants in Northern Europe (-11.8 vs. -9.5%, P=0.017).
Conclusions: The LCD significantly improved anthropometric and body composition measurements in all cities participating in DiOGenes. Objective acceptability measures should be examined in order to further explain regional differences in the effect of this diet on obesity.
|Journal||Swiss Medical Weekly|
|Publication status||Published - 2013|