Abstract
To validate a new method to identify responders (relative effect per patient (REPP) >0.2) using the OMERACT-OARSI criteria as gold standard in a large multicentre sample.The REPP ([score before - after treatment]/score before treatment) was calculated for 845 patients of a large multicenter European cohort study for THR. The patients with a REPP >0.2 were defined as responders. The responder rate was compared to the gold standard (OMERACT-OARSI criteria) using receiver operator characteristic (ROC) curve analysis for sensitivity, specificity and percentage of appropriately classified patients.With the criterion REPP>0.2 85.4% of the patients were classified as responders, applying the OARSI-OMERACT criteria 85.7%. The new method had 98.8% sensitivity, 94.2% specificity and 98.1% of the patients were correctly classified compared to the gold standard.The external validation showed a high sensitivity and also specificity of a new criterion to identify a responder compared to the gold standard method. It is simple and has no uncertainties due to a single classification criterion.
Original language | English |
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Pages (from-to) | 480-483 |
Number of pages | 4 |
Journal | Osteoarthritis and Cartilage |
Volume | 24 |
Issue number | 3 |
Early online date | 27 Oct 2015 |
DOIs | |
Publication status | Published - Mar 2016 |
Keywords
- Humans
- Osteoarthritis, Hip
- Pain Measurement
- Treatment Outcome
- Arthroplasty, Replacement, Hip
- Severity of Illness Index
- Sensitivity and Specificity
- Cohort Studies
- Reproducibility of Results
- Adult
- Aged
- Aged, 80 and over
- Middle Aged
- Female
- Male