Abstract
A convenient one-pot procedure for the preparation of pyrazoles by 1,3-dipolar cycloaddition of diazo compounds generated in situ has been developed. Diazo compounds derived from aldehydes were reacted with terminal alkynes to furnish regioselectively 3,5-disubstituted pyrazoles. Furthermore, the reaction of N-vinylimidazole and diazo compounds derived from aldehydes gave exclusively 3-substituted pyrazoles in a one-pot process.
Translated title of the contribution | 'A Novel One-pot Method for the Preparation of Pyrazoles by 1,3-Dipolar Cycloadditions of Diazo Compounds Generated in situ' |
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Original language | English |
Pages (from-to) | 5381-5383 |
Number of pages | 3 |
Journal | Journal of Organic Chemistry |
Volume | 68 |
Issue number | 13 |
DOIs | |
Publication status | Published - 27 Jun 2003 |
Keywords
- ASYMMETRIC-SYNTHESIS
- DIAZOALKANES