A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines

Jonathan Clayden*, James Clayton, Rebecca A. Harvey, Ol'Ga KarlubÍková

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

6 Citations (Scopus)

Abstract

A one-pot procedure for the synthesis of oxazolines was developed. An amino alcohol was coupled with benzoyl chlorides in the presence of triethylamine to produce a -hydroxyamide. Direct treatment with methanesulfonyl chloride forms oxazolines in good yields.

Original languageEnglish
Pages (from-to)2836-2838
Number of pages3
JournalSYNLETT
Issue number17
DOIs
Publication statusPublished - 24 Sep 2009

Keywords

  • Arenes
  • Auxiliary
  • Heterocycle substitutions
  • Oxazoline

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