A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines

Jonathan Clayden; James Clayton; Rebecca A. Harvey; Ol'Ga KarlubÍková

doi:10.1055/s-0029-1217985

A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines

Jonathan Clayden^*, James Clayton, Rebecca A. Harvey, Ol'Ga KarlubÍková

^*Corresponding author for this work

School of Chemistry

Research output: Contribution to journal › Article (Academic Journal) › peer-review

8 Citations (Scopus)

Abstract

A one-pot procedure for the synthesis of oxazolines was developed. An amino alcohol was coupled with benzoyl chlorides in the presence of triethylamine to produce a -hydroxyamide. Direct treatment with methanesulfonyl chloride forms oxazolines in good yields.

Original language	English
Pages (from-to)	2836-2838
Number of pages	3
Journal	SYNLETT
Issue number	17
DOIs	https://doi.org/10.1055/s-0029-1217985
Publication status	Published - 24 Sept 2009

Keywords

Arenes
Auxiliary
Heterocycle substitutions
Oxazoline

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@article{d466ab366fc946269f72c1f9a3d35340,

title = "A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines",

abstract = "A one-pot procedure for the synthesis of oxazolines was developed. An amino alcohol was coupled with benzoyl chlorides in the presence of triethylamine to produce a -hydroxyamide. Direct treatment with methanesulfonyl chloride forms oxazolines in good yields.",

keywords = "Arenes, Auxiliary, Heterocycle substitutions, Oxazoline",

author = "Jonathan Clayden and James Clayton and Harvey, {Rebecca A.} and Ol'Ga Karlub{\'I}kov{\'a}",

year = "2009",

month = sep,

day = "24",

doi = "10.1055/s-0029-1217985",

language = "English",

pages = "2836--2838",

journal = "SYNLETT",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

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TY - JOUR

T1 - A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines

AU - Clayden, Jonathan

AU - Clayton, James

AU - Harvey, Rebecca A.

AU - KarlubÍková, Ol'Ga

PY - 2009/9/24

Y1 - 2009/9/24

N2 - A one-pot procedure for the synthesis of oxazolines was developed. An amino alcohol was coupled with benzoyl chlorides in the presence of triethylamine to produce a -hydroxyamide. Direct treatment with methanesulfonyl chloride forms oxazolines in good yields.

AB - A one-pot procedure for the synthesis of oxazolines was developed. An amino alcohol was coupled with benzoyl chlorides in the presence of triethylamine to produce a -hydroxyamide. Direct treatment with methanesulfonyl chloride forms oxazolines in good yields.

KW - Arenes

KW - Auxiliary

KW - Heterocycle substitutions

KW - Oxazoline

UR - http://www.scopus.com/inward/record.url?scp=70449435940&partnerID=8YFLogxK

U2 - 10.1055/s-0029-1217985

DO - 10.1055/s-0029-1217985

M3 - Article (Academic Journal)

AN - SCOPUS:70449435940

SN - 0936-5214

SP - 2836

EP - 2838

JO - SYNLETT

JF - SYNLETT

IS - 17

ER -

A one-pot synthesis of 2-Aryl-4,5-anti-diphenyloxazolines

Abstract

Keywords

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