A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis

CE Garner; S Smith; PK Bardhan; NM Ratcliffe; C Probert

doi:10.1016/j.trstmh.2009.02.004

A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis

CE Garner, S Smith, PK Bardhan, NM Ratcliffe, C Probert

Research output: Contribution to journal › Article (Academic Journal) › peer-review

65 Citations (Scopus)

Abstract

The aim of this pilot study was to analyse the volatile organic compounds in faecal samples collected from cholera patients in Bangladesh to determine biomarkers that could be used for disease diagnosis. Samples were collected from patients at the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh and also from healthy controls at the same institution. The volatile organic compounds were extracted from the headspace above the sample using solid phase microextraction and analysed using gas chromatography-mass spectrometry. A biomarker was identified in the cholera samples that could be used for disease diagnosis.

Translated title of the contribution	A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis
Original language	English
Pages (from-to)	1171 - 1173
Number of pages	3
Journal	Transactions of the Royal Society and Tropical Medicine and Hygiene
Volume	103(11)
DOIs	https://doi.org/10.1016/j.trstmh.2009.02.004
Publication status	Published - Nov 2009

Bibliographical note

Publisher: Elsevier

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title = "A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis",

abstract = "The aim of this pilot study was to analyse the volatile organic compounds in faecal samples collected from cholera patients in Bangladesh to determine biomarkers that could be used for disease diagnosis. Samples were collected from patients at the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh and also from healthy controls at the same institution. The volatile organic compounds were extracted from the headspace above the sample using solid phase microextraction and analysed using gas chromatography-mass spectrometry. A biomarker was identified in the cholera samples that could be used for disease diagnosis.",

author = "CE Garner and S Smith and PK Bardhan and NM Ratcliffe and C Probert",

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year = "2009",

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doi = "10.1016/j.trstmh.2009.02.004",

language = "English",

volume = "103(11)",

pages = "1171 -- 1173",

journal = "Transactions of the Royal Society and Tropical Medicine and Hygiene",

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A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis. / Garner, CE; Smith, S; Bardhan, PK et al.
In: Transactions of the Royal Society and Tropical Medicine and Hygiene, Vol. 103(11), 11.2009, p. 1171 - 1173.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis

AU - Garner, CE

AU - Smith, S

AU - Bardhan, PK

AU - Ratcliffe, NM

AU - Probert, C

N1 - Publisher: Elsevier

PY - 2009/11

Y1 - 2009/11

N2 - The aim of this pilot study was to analyse the volatile organic compounds in faecal samples collected from cholera patients in Bangladesh to determine biomarkers that could be used for disease diagnosis. Samples were collected from patients at the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh and also from healthy controls at the same institution. The volatile organic compounds were extracted from the headspace above the sample using solid phase microextraction and analysed using gas chromatography-mass spectrometry. A biomarker was identified in the cholera samples that could be used for disease diagnosis.

AB - The aim of this pilot study was to analyse the volatile organic compounds in faecal samples collected from cholera patients in Bangladesh to determine biomarkers that could be used for disease diagnosis. Samples were collected from patients at the International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh and also from healthy controls at the same institution. The volatile organic compounds were extracted from the headspace above the sample using solid phase microextraction and analysed using gas chromatography-mass spectrometry. A biomarker was identified in the cholera samples that could be used for disease diagnosis.

U2 - 10.1016/j.trstmh.2009.02.004

DO - 10.1016/j.trstmh.2009.02.004

M3 - Article (Academic Journal)

C2 - 19268999

SN - 1878-3503

VL - 103(11)

SP - 1171

EP - 1173

JO - Transactions of the Royal Society and Tropical Medicine and Hygiene

JF - Transactions of the Royal Society and Tropical Medicine and Hygiene

ER -

A pilot study of faecal volatile organic compounds in faeces from cholera patients in Bangladesh to determine their utility in disease diagnosis

Abstract

Bibliographical note

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