A polymorphism in the CYP17 gene is associated with male breast cancer

I E Young, K M Kurian, C Annink, I H Kunkler, V A Anderson, B B Cohen, M L Hooper, A H Wyllie, C M Steel

Research output: Contribution to journalArticle (Academic Journal)

76 Citations (Scopus)

Abstract

The CYP17 gene codes for the cytochrome P450c17alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.
Original languageEnglish
Pages (from-to)141-3
Number of pages3
JournalBritish Journal of Cancer
Volume81
Issue number1
DOIs
Publication statusPublished - Sep 1999

Keywords

  • Estrogens
  • Polymorphism, Genetic
  • Humans
  • Aged
  • Breast Neoplasms
  • Genotype
  • Alleles
  • Breast Neoplasms, Male
  • Aged, 80 and over
  • Adult
  • Case-Control Studies
  • Middle Aged
  • Steroid 17-alpha-Hydroxylase
  • Female
  • Male
  • Androgens

Fingerprint Dive into the research topics of 'A polymorphism in the CYP17 gene is associated with male breast cancer'. Together they form a unique fingerprint.

Cite this