A polymorphism in the CYP17 gene is associated with male breast cancer

I E Young; K M Kurian; C Annink; I H Kunkler; V A Anderson; B B Cohen; M L Hooper; A H Wyllie; C M Steel

doi:10.1038/sj.bjc.6690663

A polymorphism in the CYP17 gene is associated with male breast cancer

I E Young, K M Kurian, C Annink, I H Kunkler, V A Anderson, B B Cohen, M L Hooper, A H Wyllie, C M Steel

Research output: Contribution to journal › Article (Academic Journal) › peer-review

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Abstract

The CYP17 gene codes for the cytochrome P450c17alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.

Original language	English
Pages (from-to)	141-3
Number of pages	3
Journal	British Journal of Cancer
Volume	81
Issue number	1
DOIs	https://doi.org/10.1038/sj.bjc.6690663
Publication status	Published - Sept 1999

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Estrogens
Polymorphism, Genetic
Humans
Aged
Breast Neoplasms
Genotype
Alleles
Breast Neoplasms, Male
Aged, 80 and over
Adult
Case-Control Studies
Middle Aged
Steroid 17-alpha-Hydroxylase
Female
Male
Androgens

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title = "A polymorphism in the CYP17 gene is associated with male breast cancer",

abstract = "The CYP17 gene codes for the cytochrome P450c17alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.",

keywords = "Estrogens, Polymorphism, Genetic, Humans, Aged, Breast Neoplasms, Genotype, Alleles, Breast Neoplasms, Male, Aged, 80 and over, Adult, Case-Control Studies, Middle Aged, Steroid 17-alpha-Hydroxylase, Female, Male, Androgens",

author = "Young, \{I E\} and Kurian, \{K M\} and C Annink and Kunkler, \{I H\} and Anderson, \{V A\} and Cohen, \{B B\} and Hooper, \{M L\} and Wyllie, \{A H\} and Steel, \{C M\}",

year = "1999",

month = sep,

doi = "10.1038/sj.bjc.6690663",

language = "English",

volume = "81",

pages = "141--3",

journal = "British Journal of Cancer",

issn = "0007-0920",

publisher = "Springer Nature",

number = "1",

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TY - JOUR

T1 - A polymorphism in the CYP17 gene is associated with male breast cancer

AU - Young, I E

AU - Kurian, K M

AU - Annink, C

AU - Kunkler, I H

AU - Anderson, V A

AU - Cohen, B B

AU - Hooper, M L

AU - Wyllie, A H

AU - Steel, C M

PY - 1999/9

Y1 - 1999/9

N2 - The CYP17 gene codes for the cytochrome P450c17alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.

AB - The CYP17 gene codes for the cytochrome P450c17alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.

KW - Estrogens

KW - Polymorphism, Genetic

KW - Humans

KW - Aged

KW - Breast Neoplasms

KW - Genotype

KW - Alleles

KW - Breast Neoplasms, Male

KW - Aged, 80 and over

KW - Adult

KW - Case-Control Studies

KW - Middle Aged

KW - Steroid 17-alpha-Hydroxylase

KW - Female

KW - Male

KW - Androgens

U2 - 10.1038/sj.bjc.6690663

DO - 10.1038/sj.bjc.6690663

M3 - Article (Academic Journal)

C2 - 10487625

SN - 0007-0920

VL - 81

SP - 141

EP - 143

JO - British Journal of Cancer

JF - British Journal of Cancer

IS - 1

ER -

A polymorphism in the CYP17 gene is associated with male breast cancer

Abstract

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Keywords

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