TY - JOUR
T1 - A systematic genomewide linkage study in 353 sib pairs with schizophrenia
AU - Williams, Nigel Melville
AU - Norton, Nadine
AU - Williams, Hywel John
AU - Ekholm, B.
AU - Hamshere, Marian Lindsay
AU - Lindblom, Y.
AU - Chowdari, K. V.
AU - Cardno, Alastair George
AU - Zammit, Stanley
AU - Jones, Lisa Anne
AU - Murphy, Kieran Christopher
AU - Sanders, Robert David
AU - McCarthy, Geraldine MaryTeresa
AU - Gray, Marion Yvonne
AU - Jones, G.
AU - Holmans, Peter Alan
AU - Nimgaonkar, V.
AU - Adolfson, R.
AU - Osby, U.
AU - Terenius, L.
AU - Sedvall, G.
AU - O'Donovan, Michael Conlon
AU - Owen, Michael John
PY - 2003/12/1
Y1 - 2003/12/1
N2 - We undertook a genomewide linkage study in a total of 353 affected sib pairs (ASPs) with schizophrenia. Our sample consisted of 179 ASPs from the United Kingdom, 134 from Sweden, and 40 from the United States. We typed 372 microsatellite markers at 10-cM intervals. Our strongest finding was a LOD score of 3.87 on chromosome 10q25.3-q26.3, with positive results being contributed by all three samples and a LOD-1 interval of 15 cM. This finding achieved genomewide significance (P
AB - We undertook a genomewide linkage study in a total of 353 affected sib pairs (ASPs) with schizophrenia. Our sample consisted of 179 ASPs from the United Kingdom, 134 from Sweden, and 40 from the United States. We typed 372 microsatellite markers at 10-cM intervals. Our strongest finding was a LOD score of 3.87 on chromosome 10q25.3-q26.3, with positive results being contributed by all three samples and a LOD-1 interval of 15 cM. This finding achieved genomewide significance (P
U2 - 10.1086/380206
DO - 10.1086/380206
M3 - Article (Academic Journal)
VL - 73
SP - 1355
EP - 1367
JO - American Journal of Human Genetics
JF - American Journal of Human Genetics
SN - 0002-9297
IS - 6
ER -