A systematic review of interventions to improve male knowledge of fertility and fertility-related risk factors

Srinithy Krishnan, Michael Daly, Ruth R Kipping, China R Harrison*

*Corresponding author for this work

Research output: Contribution to journalReview article (Academic Journal)peer-review


Male infertility is a global health concern. The effectiveness of interventions developed to improve males’ knowledge of fertility regulation and fertility-related risk factors remains unclear. This systematic review aimed to synthesize and evaluate the evidence for these interventions. Four databases were searched from inception to June 2023. Eligible studies examined interventions to increase fertility knowledge among presumed fertile males aged ≥16 years of age. Conference abstracts, protocols and studies without sex-disaggregated results for males were excluded. A narrative synthesis without meta-analysis was performed. A total of 4884 records were identified. Five studies (reported in six publications), all conducted in high-income countries, were included. Two were randomized control trials, and three were experimental studies. Interventions were delivered in person by a health professional (n = 3), online and via a mobile app. All studies showed a significant improvement in knowledge of fertility or fertility-related risk factors from baseline to follow-up. The largest improvement was observed for secondary and vocational students. A moderate, long-term retainment of knowledge was observed at two-year follow-up in one study. Available evidence suggests interventions to improve males’ fertility knowledge are effective, particularly for younger, less educated males.
Original languageEnglish
Article number2328066
JournalHuman Fertility
Issue number1
Early online date18 Mar 2024
Publication statusPublished - 18 Mar 2024

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© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.


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