Accelerometer-measured sedentary time and cardiometabolic biomarkers: A systematic review

Laura A Brocklebank; Catherine L Falconer; Angie S Page; Rachel E Perry; Ashley R Cooper

doi:10.1016/j.ypmed.2015.04.013

Accelerometer-measured sedentary time and cardiometabolic biomarkers: A systematic review

Laura A Brocklebank, Catherine L Falconer, Angie S Page, Rachel E Perry, Ashley R Cooper

Research output: Contribution to journal › Article (Academic Journal) › peer-review

189 Citations (Scopus)

443 Downloads (Pure)

Abstract

OBJECTIVE: We conducted a systematic review to investigate the cross-sectional and prospective associations of accelerometer-measured total sedentary time and breaks in sedentary time with individual cardiometabolic biomarkers in adults ≥18 years of age.

METHOD: Ovid Medline, Embase, Web of Science and the Cochrane Library were searched for studies meeting the inclusion criteria. Due to inconsistencies in the measurement and analysis of sedentary time, data was synthesised and presented narratively rather than as a meta-analysis.

RESULTS: Twenty-nine studies were included in the review; twenty-eight reported on total sedentary time and six on breaks in sedentary time. There was consistent evidence from cross-sectional data of an unfavourable association between total sedentary time and insulin sensitivity. There was also some evidence of unfavourable associations with fasting insulin, insulin resistance and triglycerides. Furthermore, there was some evidence from cross-sectional data of a favourable association between breaks in sedentary time and triglycerides.

CONCLUSION: Total sedentary time was consistently shown to be associated with poorer insulin sensitivity, even after adjusting for time spent in physical activity. This finding supports the proposed association between sedentary time and the development of Type 2 diabetes and reinforces the need to identify interventions to reduce time spent sedentary.

Original language	English
Pages (from-to)	92-102
Number of pages	11
Journal	Preventive Medicine
Volume	76
Early online date	23 Apr 2015
DOIs	https://doi.org/10.1016/j.ypmed.2015.04.013
Publication status	Published - Jul 2015

Bibliographical note

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Systematic review
Accelerometer
Sedentary time
Breaks in sedentary time
Cardiometabolic risk factors

Access to Document

10.1016/j.ypmed.2015.04.013

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Final published version, 882 KBLicence: CC BY-NC-ND

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STAMP-2: Sedentary Time and Metabolic Health in People with type 2 diabetes
Cooper, A. R. (Principal Investigator) & Page, A. S. (Co-Investigator)
1/04/12 → 31/03/17
Project: Research

Emeritus Professor Ashley R Cooper
- Ashley.Cooperbristol.acuk
- School for Policy Studies - Emeritus Professor
- Bristol Population Health Science Institute
Person: Member, Honorary and Visiting Academic

Cite this

@article{41f7921b29f646d682d3c09348796837,

title = "Accelerometer-measured sedentary time and cardiometabolic biomarkers: A systematic review",

abstract = "OBJECTIVE: We conducted a systematic review to investigate the cross-sectional and prospective associations of accelerometer-measured total sedentary time and breaks in sedentary time with individual cardiometabolic biomarkers in adults ≥18 years of age.METHOD: Ovid Medline, Embase, Web of Science and the Cochrane Library were searched for studies meeting the inclusion criteria. Due to inconsistencies in the measurement and analysis of sedentary time, data was synthesised and presented narratively rather than as a meta-analysis.RESULTS: Twenty-nine studies were included in the review; twenty-eight reported on total sedentary time and six on breaks in sedentary time. There was consistent evidence from cross-sectional data of an unfavourable association between total sedentary time and insulin sensitivity. There was also some evidence of unfavourable associations with fasting insulin, insulin resistance and triglycerides. Furthermore, there was some evidence from cross-sectional data of a favourable association between breaks in sedentary time and triglycerides.CONCLUSION: Total sedentary time was consistently shown to be associated with poorer insulin sensitivity, even after adjusting for time spent in physical activity. This finding supports the proposed association between sedentary time and the development of Type 2 diabetes and reinforces the need to identify interventions to reduce time spent sedentary.",

keywords = "Systematic review, Accelerometer, Sedentary time, Breaks in sedentary time, Cardiometabolic risk factors",

author = "Brocklebank, \{Laura A\} and Falconer, \{Catherine L\} and Page, \{Angie S\} and Perry, \{Rachel E\} and Cooper, \{Ashley R\}",

note = "Copyright {\textcopyright} 2015. Published by Elsevier Inc.",

year = "2015",

month = jul,

doi = "10.1016/j.ypmed.2015.04.013",

language = "English",

volume = "76",

pages = "92--102",

journal = "Preventive Medicine",

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T1 - Accelerometer-measured sedentary time and cardiometabolic biomarkers

T2 - A systematic review

AU - Brocklebank, Laura A

AU - Falconer, Catherine L

AU - Page, Angie S

AU - Perry, Rachel E

AU - Cooper, Ashley R

PY - 2015/7

Y1 - 2015/7

N2 - OBJECTIVE: We conducted a systematic review to investigate the cross-sectional and prospective associations of accelerometer-measured total sedentary time and breaks in sedentary time with individual cardiometabolic biomarkers in adults ≥18 years of age.METHOD: Ovid Medline, Embase, Web of Science and the Cochrane Library were searched for studies meeting the inclusion criteria. Due to inconsistencies in the measurement and analysis of sedentary time, data was synthesised and presented narratively rather than as a meta-analysis.RESULTS: Twenty-nine studies were included in the review; twenty-eight reported on total sedentary time and six on breaks in sedentary time. There was consistent evidence from cross-sectional data of an unfavourable association between total sedentary time and insulin sensitivity. There was also some evidence of unfavourable associations with fasting insulin, insulin resistance and triglycerides. Furthermore, there was some evidence from cross-sectional data of a favourable association between breaks in sedentary time and triglycerides.CONCLUSION: Total sedentary time was consistently shown to be associated with poorer insulin sensitivity, even after adjusting for time spent in physical activity. This finding supports the proposed association between sedentary time and the development of Type 2 diabetes and reinforces the need to identify interventions to reduce time spent sedentary.

AB - OBJECTIVE: We conducted a systematic review to investigate the cross-sectional and prospective associations of accelerometer-measured total sedentary time and breaks in sedentary time with individual cardiometabolic biomarkers in adults ≥18 years of age.METHOD: Ovid Medline, Embase, Web of Science and the Cochrane Library were searched for studies meeting the inclusion criteria. Due to inconsistencies in the measurement and analysis of sedentary time, data was synthesised and presented narratively rather than as a meta-analysis.RESULTS: Twenty-nine studies were included in the review; twenty-eight reported on total sedentary time and six on breaks in sedentary time. There was consistent evidence from cross-sectional data of an unfavourable association between total sedentary time and insulin sensitivity. There was also some evidence of unfavourable associations with fasting insulin, insulin resistance and triglycerides. Furthermore, there was some evidence from cross-sectional data of a favourable association between breaks in sedentary time and triglycerides.CONCLUSION: Total sedentary time was consistently shown to be associated with poorer insulin sensitivity, even after adjusting for time spent in physical activity. This finding supports the proposed association between sedentary time and the development of Type 2 diabetes and reinforces the need to identify interventions to reduce time spent sedentary.

KW - Systematic review

KW - Accelerometer

KW - Sedentary time

KW - Breaks in sedentary time

KW - Cardiometabolic risk factors

U2 - 10.1016/j.ypmed.2015.04.013

DO - 10.1016/j.ypmed.2015.04.013

M3 - Article (Academic Journal)

C2 - 25913420

SN - 0091-7435

VL - 76

SP - 92

EP - 102

JO - Preventive Medicine

JF - Preventive Medicine

ER -

Accelerometer-measured sedentary time and cardiometabolic biomarkers: A systematic review

Abstract

Bibliographical note

UN SDGs

Keywords

Access to Document

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Projects

STAMP-2: Sedentary Time and Metabolic Health in People with type 2 diabetes

Profiles

Emeritus Professor Ashley R Cooper

Cite this