TY - JOUR
T1 - Achieving conformational control over C-C, C-N and C-O bonds in biaryls, N,N′-diarylureas and diaryl ethers
T2 - Advantages of a relay axis
AU - Betson, Mark S.
AU - Bracegirdle, Ann
AU - Clayden, Jonathan
AU - Helliwell, Madeleine
AU - Lund, Andrew
AU - Pickworth, Mark
AU - Snape, Timothy J.
AU - Worrall, Christopher P.
PY - 2007/2/21
Y1 - 2007/2/21
N2 - The orientation of Ar-C, Ar-N and Ar-O bonds in biaryls, N,N′-diarylureas and diaryl ethers (whose conformers are distinguishable by NMR) may be controlled with a selectivity up to >95: 5 by an adjacent stereogenic centre; the selectivity may be greater when a second stereogenic axis is inserted between the controlling centre and the slowly rotating bond.
AB - The orientation of Ar-C, Ar-N and Ar-O bonds in biaryls, N,N′-diarylureas and diaryl ethers (whose conformers are distinguishable by NMR) may be controlled with a selectivity up to >95: 5 by an adjacent stereogenic centre; the selectivity may be greater when a second stereogenic axis is inserted between the controlling centre and the slowly rotating bond.
UR - http://www.scopus.com/inward/record.url?scp=33846932037&partnerID=8YFLogxK
U2 - 10.1039/b614618j
DO - 10.1039/b614618j
M3 - Article (Academic Journal)
C2 - 17392973
AN - SCOPUS:33846932037
SN - 1359-7345
SP - 754
EP - 756
JO - Chemical Communications
JF - Chemical Communications
IS - 7
ER -