Activation by sub-stoichiometric inhibition

Melisa Merdanovic, Steven G Burston, Anna Laura Schmitz, Steffen Köcher, Stefan Knapp, Tim Clausen, Markus Kaiser, Robert Huber, Michael Ehrmann

Research output: Contribution to journal › Article (Academic Journal) › peer-review

8 Citations (Scopus)
205 Downloads (Pure)
Original languageEnglish
Pages (from-to)1414-1418
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume117
Issue number3
Early online date6 Jan 2020
DOIs
Publication statusPublished - 21 Jan 2020

Keywords

  • HtrA protease
  • allostery
  • cooperativity
  • HTRA1
  • inhibitor

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  • Full-text PDF (author’s accepted manuscript)

    This is the author accepted manuscript (AAM). The final published version (version of record) is available online via National Academy of Sciences at https://doi.org/10.1073/pnas.1918721117 . Please refer to any applicable terms of use of the publisher.

    Accepted author manuscript, 757 KB
  • Supplementary information PDF

    This is the author accepted manuscript (AAM). The final published version (version of record) is available online via National Academy of Sciences at https://doi.org/10.1073/pnas.1918721117. Please refer to any applicable terms of use of the publisher.

    Accepted author manuscript, 3.77 MB
  • Full-text PDF (final published version)

    This is the final published version of the article (version of record). It first appeared online via National Academy of Sciences at https://doi.org/10.1073/pnas.1918721117 . Please refer to any applicable terms of use of the publisher.

    Final published version, 1.11 MB

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