Projects per year
AIMS: To investigate the relationship between cannabis and tobacco use by age 15 and subsequent educational outcomes.
DESIGN: Birth cohort study SETTING: England PARTICIPANTS: The sample was drawn from the Avon Longitudinal Study of Parents and Children; a core sample of 1,155 individuals had complete information on all the variables.
MEASUREMENTS: Main exposures were cannabis and tobacco use at age 15 assessed in clinic by computer assisted questionnaire and serum cotinine. Main outcomes were performance in standardised assessments at 16 (Key Stage Four, GCSE) in English and mathematics (mean scores), completion of five or more assessments at grade C level or higher and leaving school having achieved no qualifications. Analyses were sequentially adjusted for multiple covariates using a hierarchical approach. Covariates considered were: maternal substance use (ever tobacco or cannabis use, alcohol use above recommended limits) ; life course socio-economic position (family occupational class, maternal education, family income); child sex; month and year of birth; child educational attainment prior to age 11 (Key Stage 2); child substance use (tobacco, alcohol and cannabis) prior to age 15 and child conduct disorder.
FINDINGS: In fully adjusted models both cannabis and tobacco use at age 15 were associated with subsequent adverse educational outcomes. In general the dose response effect seen was consistent across all educational outcomes assessed. Weekly cannabis use was negatively associated with English GCSE results (Grade Point Difference [GPD], -5.93, 95% CI, -8.34, -3.53) and with mathematics GCSE results (GPD, -6.91, 95% CI, -9.92, -3.89). Daily tobacco smoking was negatively associated with English GCSE (GPD, -11.90, 95% CI, -13.47, -10.33) and with mathematics GCSE (GPD, -16.72, 95% CI, -18.57, -14.86). The greatest attenuation of these effects was seen on adjustment for other substance use and conduct disorder. Following adjustment tobacco appeared to have a consistently stronger effect than cannabis.
CONCLUSIONS: Both cannabis and tobacco use in adolescence are strongly associated with subsequent adverse educational outcomes. Given the non-specific patterns of association seen and the attenuation of estimates on adjustment it is possible that these effects arise through non-causal mechanisms, although a causal explanation cannot be discounted. This article is protected by copyright. All rights reserved.
Bibliographical noteThis article is protected by copyright. All rights reserved.
- Brain and Behaviour
- Tobacco and Alcohol
1/06/15 → 31/05/20
1/05/09 → 1/04/13
- Bristol Medical School (PHS) - Professor in Clinical Epidemiology and Primary Care & Joint Head of CAPC
- Bristol Population Health Science Institute
- Health Protection Research Unit (HPRU)
- Infection and Immunity
- Centre for Academic Primary Care
Person: Academic , Member