Advising patients seeking stem cell interventions for multiple sclerosis

Beatrice Von Wunster, Steven Bailey, Alastair Wilkins, David I. Marks, Neil J. Scolding, Claire M. Rice*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

3 Citations (Scopus)
421 Downloads (Pure)

Abstract

Given the intuitive potential of stem cell therapy and limitations of current treatment options for progressive multiple sclerosis (MS), it is not surprising that patients consider undertaking significant clinical and financial risks to access stem cell transplantation. However, while increasing evidence supports autologous haematopoietic stem cell transplantation (AHSCT) in aggressive relapsing-remitting MS, interventions employing haematopoietic or other stem cells should otherwise be considered experimental and recommended only in the context of a properly regulated clinical study. Understandably, most neurologists are unfamiliar with AHSCT procedures and the specific requirements for quality assurance and safety standards, as well as post-procedure precautions and follow-up. Consequently they may feel ill-equipped to advise patients. Here, we highlight important points for discussion in consultations with patients considering stem cell € tourism' for MS.

Original languageEnglish
Number of pages5
JournalPractical Neurology
Early online date30 May 2018
DOIs
Publication statusE-pub ahead of print - 30 May 2018

Keywords

  • cell therapy
  • haematopoietic stem cell transplanation
  • multiple sclerosis
  • stem cells

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