Alanine aminotransferase, gamma-glutamyltransferase (GGT) and all-cause mortality: results from a population-based Danish twins study alanine aminotransferase, GGT and mortality in elderly twins

Abigail Fraser, Mikael Thinggaard, Kaare Christensen, Debbie A Lawlor

Research output: Contribution to journalArticle (Academic Journal)peer-review

24 Citations (Scopus)

Abstract

Alanine aminotransferase (ALT) and gamma-glutamyltransferase (GGT) are widely used markers of liver disease. Several population-based cohort studies have found associations of these liver enzymes with all-cause mortality. None of these studies controlled for genetic variation as well as fetal and early life exposure, whether environmental or genetic.
Original languageEnglish
Pages (from-to)1494-9
Number of pages6
JournalLiver International
Volume29
Issue number10
DOIs
Publication statusPublished - Nov 2009

Keywords

  • Aged
  • Aged, 80 and over
  • Alanine Transaminase
  • Cardiovascular Diseases
  • Diabetes Mellitus
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Mortality
  • Proportional Hazards Models
  • gamma-Glutamyltransferase

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