Alpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease

Anna Maria Colacicco, Vincenzo Solfrizzi, Alessia D'Introno, Cristiano Capurso, Patrick G Kehoe, Davide Seripa, Alberto Pilotto, Andrea Santamato, Antonio Capurso, Francesco Panza

Research output: Contribution to journalArticle (Academic Journal)peer-review

9 Citations (Scopus)

Abstract

A total sample of 169 AD patients, and 264 age- and sex-matched unrelated caregivers from Apulia, southern Italy, were genotypized for alpha-2-macroglobulin (A2M) Val1000/Ile single-nucleotide polymorphism (SNP) (rs669), apolipoprotein E (APOE), and SNPs (+1073 and +1071) in the oxidized low-density lipoprotein receptor-1 (OLR1) gene on chromosome 12. A2M allele and genotype frequencies were similar between AD patients and controls, also after stratification for late onset (>/=70 years) and early onset (
Translated title of the contributionAlpha-2-macroglobulin gene, oxidized low-density lipoprotein receptor-1 locus, and sporadic Alzheimer's disease
Original languageEnglish
Pages (from-to)1518 - 1520
Number of pages3
JournalNeurobiology of Aging
Volume30
Issue number9
DOIs
Publication statusPublished - Sep 2009

Bibliographical note

Publisher: Elsevier

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