Altered left ventricular diastolic filling following a marathon is a reproducible phenomenon

Natalie Middleton, Rob Shave, Keith George, Gregory Whyte, Emma Hart, David Oxborough, Jan Forster, David Gaze

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)


The present study examined the reproducibility of alterations in left ventricular function and cardiac biomarkers in a cohort of athletes following two marathons, one year apart. Eight participants in the 2004 and 2005 London Marathons were tested pre- and post-race via echocardiography and humoral analysis. Reductions in diastolic filling, unrelated to loading or heart rate, following both marathons were reproducible within individuals, which may be a function of exercise duration. In contrast, exercise-induced cardiac troponin release was inconsistent.

Original languageEnglish
Pages (from-to)87-9
Number of pages3
JournalInternational Journal of Cardiology
Issue number1
Publication statusPublished - 31 Oct 2007



  • Adult
  • Cohort Studies
  • Humans
  • Reproducibility of Results
  • Running
  • Stroke Volume
  • Ventricular Function, Left

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