Projects per year
Abstract
In this study, we report the production of amine functionalized nanodiamond. The amine
functionalized nanodiamond forms a conformal monolayer on a negatively charged surface
produced via plasma polymerization of acrylic acid. Nanodiamond terminated surfaces were
studied as substrates for neuronal cell culture. NG108-15 neuroblastoma-glyoma hybrid
cells were successfully cultured upon amine functionalized nanodiamond coated surfaces for
between 1 and 7 d. Additionally, primary dorsal root ganglion (DRG) neurons and Schwann
cells isolated from Wistar rats were also successfully cultured over a period of 21 d illustrating
the potential of the coating for applications in the treatment of peripheral nerve injury.
functionalized nanodiamond forms a conformal monolayer on a negatively charged surface
produced via plasma polymerization of acrylic acid. Nanodiamond terminated surfaces were
studied as substrates for neuronal cell culture. NG108-15 neuroblastoma-glyoma hybrid
cells were successfully cultured upon amine functionalized nanodiamond coated surfaces for
between 1 and 7 d. Additionally, primary dorsal root ganglion (DRG) neurons and Schwann
cells isolated from Wistar rats were also successfully cultured over a period of 21 d illustrating
the potential of the coating for applications in the treatment of peripheral nerve injury.
Original language | English |
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Pages (from-to) | 045009 |
Number of pages | 11 |
Journal | Biomedical Materials (Bristol) |
Volume | 9 |
DOIs | |
Publication status | Published - 2014 |
Keywords
- Diamondlike carbon
- Neurons
Fingerprint Dive into the research topics of 'Amine functionalized nanodiamond promotes cellular adhesion, proliferation and neurite outgrowth'. Together they form a unique fingerprint.
Projects
- 1 Finished
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CVD DIAMOND AS A SUBSTRATE FOR BIOLOGICAL CELL GROWTH - TOWARDS DIRECT BRAIN-COMPUTER INTERFACES
18/02/13 → 18/06/16
Project: Research