An accessible bicyclic architecture for synthetic lectins

Joshua D. Howgego; Craig P. Butts; Matthew P. Crump; Anthony P. Davis

doi:10.1039/c3cc41190g

An accessible bicyclic architecture for synthetic lectins

Joshua D. Howgego, Craig P. Butts, Matthew P. Crump, Anthony P. Davis^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

17 Citations (Scopus)

Abstract

Bicyclic carbohydrate receptors are easier to synthesise than tri- or tetra-cyclic relatives, and are better adapted to bind monosaccharide residues with bulky appendages. Disaccharides containing beta-glucosyl units are preferred substrates.

Original language	English
Pages (from-to)	3110-3112
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	30
DOIs	https://doi.org/10.1039/c3cc41190g
Publication status	Published - 2013

Research Groups and Themes

Organic & Biological

Keywords

WATER
BINDING
CARBOHYDRATE-RECOGNITION
RECEPTORS
AGGLUTININ
DISACCHARIDE

Access to Document

10.1039/c3cc41190g

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3-month Core Capability for Chemistry Research
Crosby, J. (Principal Investigator)
1/01/13 → 1/04/13
Project: Research
SYNTHETIC LECTIS FOR OLIGOSACCHARIDE BINDING IN AQUEOUS MEDIA
Davis, A. P. (Principal Investigator)
1/06/06 → 1/08/09
Project: Research

Cite this

@article{903e6118bb7b4a38a1772fc263df154d,

title = "An accessible bicyclic architecture for synthetic lectins",

abstract = "Bicyclic carbohydrate receptors are easier to synthesise than tri- or tetra-cyclic relatives, and are better adapted to bind monosaccharide residues with bulky appendages. Disaccharides containing beta-glucosyl units are preferred substrates.",

keywords = "WATER, BINDING, CARBOHYDRATE-RECOGNITION, RECEPTORS, AGGLUTININ, DISACCHARIDE",

author = "Howgego, \{Joshua D.\} and Butts, \{Craig P.\} and Crump, \{Matthew P.\} and Davis, \{Anthony P.\}",

year = "2013",

doi = "10.1039/c3cc41190g",

language = "English",

volume = "49",

pages = "3110--3112",

journal = "Chemical Communications",

issn = "1364-548X",

publisher = "Royal Society of Chemistry",

number = "30",

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TY - JOUR

T1 - An accessible bicyclic architecture for synthetic lectins

AU - Howgego, Joshua D.

AU - Butts, Craig P.

AU - Crump, Matthew P.

AU - Davis, Anthony P.

PY - 2013

Y1 - 2013

N2 - Bicyclic carbohydrate receptors are easier to synthesise than tri- or tetra-cyclic relatives, and are better adapted to bind monosaccharide residues with bulky appendages. Disaccharides containing beta-glucosyl units are preferred substrates.

AB - Bicyclic carbohydrate receptors are easier to synthesise than tri- or tetra-cyclic relatives, and are better adapted to bind monosaccharide residues with bulky appendages. Disaccharides containing beta-glucosyl units are preferred substrates.

KW - WATER

KW - BINDING

KW - CARBOHYDRATE-RECOGNITION

KW - RECEPTORS

KW - AGGLUTININ

KW - DISACCHARIDE

U2 - 10.1039/c3cc41190g

DO - 10.1039/c3cc41190g

M3 - Article (Academic Journal)

C2 - 23478469

SN - 1364-548X

SN - 2050-5639

VL - 49

SP - 3110

EP - 3112

JO - Chemical Communications

JF - Chemical Communications

IS - 30

ER -

An accessible bicyclic architecture for synthetic lectins

Abstract

Research Groups and Themes

Keywords

Access to Document

Handle.net

Fingerprint

Projects

3-month Core Capability for Chemistry Research

SYNTHETIC LECTIS FOR OLIGOSACCHARIDE BINDING IN AQUEOUS MEDIA

Cite this