An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth

Jason Potticary; Lui R. Terry; Chris Bell; Alexandros N. Papanikolopoulos; Peter C. M. Christianen; Hans Engelkamp; Andrew M. Collins; Claudio Fontanesi; Gabriele Kociok-Köhn; Simon Crampin; Enrico da Como; Simon R. Hall

doi:10.1038/ncomms11555

An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth

Jason Potticary
, Lui R. Terry
, Chris Bell
, Alexandros N. Papanikolopoulos
, Peter C. M. Christianen
, Hans Engelkamp
, Andrew M. Collins
, Claudio Fontanesi
, Gabriele Kociok-Köhn
, Simon Crampin
, Enrico da Como
, Simon R. Hall^*

^*Corresponding author for this work

Research output: Contribution to journal › Article (Academic Journal) › peer-review

83 Citations (Scopus)

469 Downloads (Pure)

Abstract

The continued development of novel drugs, proteins, and advanced materials strongly rely on our ability to self-assemble molecules in solids with the most suitable structure (polymorph) in order to exhibit desired functionalities. The search for new polymorphs remains a scientific challenge, that is at the core of crystal engineering and there has been a lack of effective solutions to this problem. Here we show that by crystallizing the polyaromatic hydrocarbon coronene in the presence of a magnetic field, a polymorph is formed in a β-herringbone structure instead of the ubiquitous 3-herringbone structure, with a decrease of 35° in the herringbone nearest neighbour angle. The β-herringbone polymorph is stable, preserves its structure under ambient conditions and as a result of the altered molecular packing of the crystals, exhibits significant changes to the optical and mechanical properties of the crystal.

Original language	English
Article number	11555
Number of pages	7
Journal	Nature Communications
Volume	7
Early online date	10 May 2016
DOIs	https://doi.org/10.1038/ncomms11555
Publication status	Published - 10 May 2016

Research Groups and Themes

Bristol BioDesign Institute
Inorganic & Materials

Keywords

synthetic biology
Coronene
Polyaromatic hydrocarbon
Crystal-growth
Polymorphism

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10.1038/ncomms11555

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Final published version, 1.56 MBLicence: CC BY

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Potticary, J., Terry, L. R., Bell, C., Papanikolopoulos, A. N., Christianen, P. C. M., Engelkamp, H., Collins, A. M., Fontanesi, C., Kociok-Köhn, G., Crampin, S., da Como, E., & Hall, S. R. (2016). An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth. Nature Communications, 7, Article 11555. https://doi.org/10.1038/ncomms11555

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title = "An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth",

abstract = "The continued development of novel drugs, proteins, and advanced materials strongly rely on our ability to self-assemble molecules in solids with the most suitable structure (polymorph) in order to exhibit desired functionalities. The search for new polymorphs remains a scientific challenge, that is at the core of crystal engineering and there has been a lack of effective solutions to this problem. Here we show that by crystallizing the polyaromatic hydrocarbon coronene in the presence of a magnetic field, a polymorph is formed in a β-herringbone structure instead of the ubiquitous 3-herringbone structure, with a decrease of 35° in the herringbone nearest neighbour angle. The β-herringbone polymorph is stable, preserves its structure under ambient conditions and as a result of the altered molecular packing of the crystals, exhibits significant changes to the optical and mechanical properties of the crystal.",

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author = "Jason Potticary and Terry, \{Lui R.\} and Chris Bell and Papanikolopoulos, \{Alexandros N.\} and Christianen, \{Peter C. M.\} and Hans Engelkamp and Collins, \{Andrew M.\} and Claudio Fontanesi and Gabriele Kociok-K{\"o}hn and Simon Crampin and \{da Como\}, Enrico and Hall, \{Simon R.\}",

year = "2016",

month = may,

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doi = "10.1038/ncomms11555",

language = "English",

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journal = "Nature Communications",

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AU - Papanikolopoulos, Alexandros N.

AU - Christianen, Peter C. M.

AU - Engelkamp, Hans

AU - Collins, Andrew M.

AU - Fontanesi, Claudio

AU - Kociok-Köhn, Gabriele

AU - Crampin, Simon

AU - da Como, Enrico

AU - Hall, Simon R.

PY - 2016/5/10

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N2 - The continued development of novel drugs, proteins, and advanced materials strongly rely on our ability to self-assemble molecules in solids with the most suitable structure (polymorph) in order to exhibit desired functionalities. The search for new polymorphs remains a scientific challenge, that is at the core of crystal engineering and there has been a lack of effective solutions to this problem. Here we show that by crystallizing the polyaromatic hydrocarbon coronene in the presence of a magnetic field, a polymorph is formed in a β-herringbone structure instead of the ubiquitous 3-herringbone structure, with a decrease of 35° in the herringbone nearest neighbour angle. The β-herringbone polymorph is stable, preserves its structure under ambient conditions and as a result of the altered molecular packing of the crystals, exhibits significant changes to the optical and mechanical properties of the crystal.

AB - The continued development of novel drugs, proteins, and advanced materials strongly rely on our ability to self-assemble molecules in solids with the most suitable structure (polymorph) in order to exhibit desired functionalities. The search for new polymorphs remains a scientific challenge, that is at the core of crystal engineering and there has been a lack of effective solutions to this problem. Here we show that by crystallizing the polyaromatic hydrocarbon coronene in the presence of a magnetic field, a polymorph is formed in a β-herringbone structure instead of the ubiquitous 3-herringbone structure, with a decrease of 35° in the herringbone nearest neighbour angle. The β-herringbone polymorph is stable, preserves its structure under ambient conditions and as a result of the altered molecular packing of the crystals, exhibits significant changes to the optical and mechanical properties of the crystal.

KW - synthetic biology

KW - Coronene

KW - Polyaromatic hydrocarbon

KW - Crystal-growth

KW - Polymorphism

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DO - 10.1038/ncomms11555

M3 - Article (Academic Journal)

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SN - 2041-1723

VL - 7

JO - Nature Communications

JF - Nature Communications

M1 - 11555

ER -

An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth

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Professor Simon R Hall

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An unforeseen polymorph of coronene by the application of magnetic fields during crystal growth

Abstract

Research Groups and Themes

Keywords

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Embargoed Document

Embargoed Document

Fingerprint

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3-month Core Capability for Chemistry Research

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Professor Simon R Hall

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