Antibiotic prophylaxis for bacterial infections in afebrile neutropenic patients following chemotherapy

Anat Gafter-Gvili, Abigail Fraser, Mical Paul, Liat Vidal, Theresa A Lawrie, Marianne D van de Wetering, Leontien C M Kremer, Leonard Leibovici

Research output: Contribution to journalArticle (Academic Journal)peer-review

207 Citations (Scopus)

Abstract

Bacterial infections are a major cause of morbidity and mortality in patients who are neutropenic following chemotherapy for malignancy. Trials have shown the efficacy of antibiotic prophylaxis in reducing the incidence of bacterial infections but not in reducing mortality rates. Our systematic review from 2006 also showed a reduction in mortality.
Original languageEnglish
Pages (from-to)CD004386
JournalCochrane Database of Systematic Reviews
Volume1
DOIs
Publication statusPublished - 2012

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