Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents

Adrian G Flint, Emmanuella Bema Twumasi, Pearl Ihuoma Akazue, Kwaku Kyeremeh, Theresa Manful Gwira, Jennifer Keiser, Fidelis Cho-Ngwa, Dorcas Osei-Safo

Research output: Contribution to journalArticle (Academic Journal)peer-review

Abstract

Ghana is endemic for some neglected tropical diseases (NTDs) including schistosomiasis, onchocerciasis and lymphatic filariasis. The major intervention for these diseases is mass drug administration of a few repeatedly recycled drugs which is a cause for major concern due to reduced efficacy of the drugs and the emergence of drug resistance. Evidently, new treatments are needed urgently. Medicinal plants, on the other hand, have a reputable history as important sources of potent therapeutic agents in the treatment of various diseases among African populations, Ghana inclusively, and provide very useful starting points for the discovery of much-needed new or alternative drugs.
Original languageEnglish
JournalPLoS Neglected Tropical Diseases
Volume14
Issue number12
DOIs
Publication statusPublished - 31 Dec 2020

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