Apoptosis and Cell Death

Angela Hague

Apoptosis and Cell Death

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Abstract

The aim of this Chapter is to summarise current understanding of apoptosis and cell death from a clinical perspective, focussing on the head and neck. Recent or landmark reviews have been selected for importance or clear explanations. The basis behind some of the methods to measure cell death is explained to assist in evaluating primary research papers. Emphasis is placed on the role of evasion of apoptosis in head and neck squamous cell carcinoma (HNSCC), although the role of cell death in other processes may be of interest to the specialist clinician, for example: cancers of the head and neck; head and neck development; palatal shelf fusion and cleft palate; autoimmune disease; and hearing loss due to aging, noise, or exposure to ototoxic agents. Keywords used in PubMed included HNSCC, oropharyngeal, apoptosis, necroptosis, autophagy, senescence, radioresistance, p53, HPV (human papilloma virus), cetuximab, EGFR (epidermal growth factor receptor).

Original language	English
Title of host publication	Scott Brown's Otorhinolaryngology and Head and Neck Surgery
Editors	John C Watkinson, Ray W Clarke
Publisher	CRC Press
Chapter	6
Volume	1
Edition	8th
ISBN (Electronic)	9781138094611
Publication status	Published - 17 Sep 2018

Fingerprint Dive into the research topics of 'Apoptosis and Cell Death'. Together they form a unique fingerprint.

Cite this

@inbook{fcf2fc6febb04c1987d57fea82cb6715,

title = "Apoptosis and Cell Death",

abstract = "The aim of this Chapter is to summarise current understanding of apoptosis and cell death from a clinical perspective, focussing on the head and neck. Recent or landmark reviews have been selected for importance or clear explanations. The basis behind some of the methods to measure cell death is explained to assist in evaluating primary research papers. Emphasis is placed on the role of evasion of apoptosis in head and neck squamous cell carcinoma (HNSCC), although the role of cell death in other processes may be of interest to the specialist clinician, for example: cancers of the head and neck; head and neck development; palatal shelf fusion and cleft palate; autoimmune disease; and hearing loss due to aging, noise, or exposure to ototoxic agents. Keywords used in PubMed included HNSCC, oropharyngeal, apoptosis, necroptosis, autophagy, senescence, radioresistance, p53, HPV (human papilloma virus), cetuximab, EGFR (epidermal growth factor receptor).",

author = "Angela Hague",

year = "2018",

month = sep,

day = "17",

language = "English",

volume = "1",

editor = "Watkinson, {John C} and Clarke, {Ray W}",

booktitle = "Scott Brown's Otorhinolaryngology and Head and Neck Surgery",

publisher = "CRC Press",

address = "United States",

edition = "8th",

}

TY - CHAP

T1 - Apoptosis and Cell Death

AU - Hague, Angela

PY - 2018/9/17

Y1 - 2018/9/17

N2 - The aim of this Chapter is to summarise current understanding of apoptosis and cell death from a clinical perspective, focussing on the head and neck. Recent or landmark reviews have been selected for importance or clear explanations. The basis behind some of the methods to measure cell death is explained to assist in evaluating primary research papers. Emphasis is placed on the role of evasion of apoptosis in head and neck squamous cell carcinoma (HNSCC), although the role of cell death in other processes may be of interest to the specialist clinician, for example: cancers of the head and neck; head and neck development; palatal shelf fusion and cleft palate; autoimmune disease; and hearing loss due to aging, noise, or exposure to ototoxic agents. Keywords used in PubMed included HNSCC, oropharyngeal, apoptosis, necroptosis, autophagy, senescence, radioresistance, p53, HPV (human papilloma virus), cetuximab, EGFR (epidermal growth factor receptor).

AB - The aim of this Chapter is to summarise current understanding of apoptosis and cell death from a clinical perspective, focussing on the head and neck. Recent or landmark reviews have been selected for importance or clear explanations. The basis behind some of the methods to measure cell death is explained to assist in evaluating primary research papers. Emphasis is placed on the role of evasion of apoptosis in head and neck squamous cell carcinoma (HNSCC), although the role of cell death in other processes may be of interest to the specialist clinician, for example: cancers of the head and neck; head and neck development; palatal shelf fusion and cleft palate; autoimmune disease; and hearing loss due to aging, noise, or exposure to ototoxic agents. Keywords used in PubMed included HNSCC, oropharyngeal, apoptosis, necroptosis, autophagy, senescence, radioresistance, p53, HPV (human papilloma virus), cetuximab, EGFR (epidermal growth factor receptor).

M3 - Chapter in a book

VL - 1

BT - Scott Brown's Otorhinolaryngology and Head and Neck Surgery

A2 - Watkinson, John C

A2 - Clarke, Ray W

PB - CRC Press

ER -