TY - JOUR
T1 - Application of Mendelian randomization
T2 - can we establish causal risk factors for type 2 diabetes in low-to-middle income countries?
AU - Langdon, Ryan
AU - Wade, Kaitlin
PY - 2017/1/1
Y1 - 2017/1/1
N2 - The global burden of type 2 diabetes (T2D) is increasing, partially facilitated by a sharp increase in the disease in low and middle income countries (LMICs). LMICs not only show a high prevalence of T2D (8.7%), but have shown a much faster increase in this prevalence over the past 30 years when compared to high-income countries (HICs). Conventional risk factors for T2D in HICs, such as high body mass index (BMI), low levels of physical activity, and poor dietary behaviours, do not fully account for the greater increase in prevalence of T2D in LMICs. Therefore, risk factors for T2D specifically within an LMIC context need to be determined.
AB - The global burden of type 2 diabetes (T2D) is increasing, partially facilitated by a sharp increase in the disease in low and middle income countries (LMICs). LMICs not only show a high prevalence of T2D (8.7%), but have shown a much faster increase in this prevalence over the past 30 years when compared to high-income countries (HICs). Conventional risk factors for T2D in HICs, such as high body mass index (BMI), low levels of physical activity, and poor dietary behaviours, do not fully account for the greater increase in prevalence of T2D in LMICs. Therefore, risk factors for T2D specifically within an LMIC context need to be determined.
U2 - 10.15649/cuidarte.v8i1.373
DO - 10.15649/cuidarte.v8i1.373
M3 - Review article (Academic Journal)
SN - 2216-0973
VL - 8
SP - 1391
EP - 1406
JO - Revista Cuidarte
JF - Revista Cuidarte
IS - 1
ER -