Abstract
Catalytic and stoichiometric asymmetric sulfur ylide reactions were employed to prepare alkyl-aryl epoxide intermediates in a convergent manner. These epoxides were utilized in efficient syntheses of the mevinic acid analogue 1 and prelactone B. (C) 2004 Elsevier Ltd. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 9725-9733 |
| Number of pages | 9 |
| Journal | Tetrahedron |
| Volume | 60 |
| Issue number | 43 |
| DOIs | |
| Publication status | Published - 18 Oct 2004 |
Research Groups and Themes
- Organic & Biological
Keywords
- sulfur ylide
- epoxides
- mevinic acid
- IN-SITU GENERATION
- PRELACTONE-B
- ENANTIOSELECTIVE SYNTHESIS
- 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE
- PHOSPHAZENE BASE
- DIAZO-COMPOUNDS
- EPOXIDES
- (+)-COMPACTIN
- INHIBITORS
- MEVINOLIN
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