Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis

Viki Worth; Rachel Perry; Anthony Ireland; Andrew Wills; Jonathan Sandy; Andrew R Ness

doi:10.1038/sj.bdj.2017.581

Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis

Viki Worth, Rachel Perry, Anthony Ireland, Andrew Wills, Jonathan Sandy, Andrew R Ness

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Abstract

Objective To establish whether children born with an orofacial cleft have a higher risk of dental caries than individuals without cleft.

Design A systematic review and meta-analysis

Methods The search strategy was based on the key words 'cleft lip palate' and 'oral hygiene caries decay'. Ten databases were searched from their inception to April 2016 to identify all relevant studies. All data were extracted by two independent reviewers. The primary outcome measure was caries measured by the decayed, missing, filled surfaces/teeth index (dmfs/dmft or DMFS/DMFT).

Results Twenty-four studies met the selection criteria. All of the studies were observational. Twenty-two studies were suitable for inclusion in the meta-analysis. The overall pooled mean difference in dmft was 0.63 (95% CI: 0.47 to 0.79) and in DMFT was 0.28 (95% CI: 0.22 to 0.34).Conclusion Individuals with cleft lip and/or palate have higher caries prevalence, both in the deciduous and the permanent dentitions.

Original language	English
Pages (from-to)	37-47
Number of pages	11
Journal	British Dental Journal
Volume	223
Issue number	1
Early online date	7 Jul 2017
DOIs	https://doi.org/10.1038/sj.bdj.2017.581
Publication status	Published - Jul 2017

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NIHR BRC Nutrition
Ness, A. R. (Principal Investigator)
1/04/17 → 31/03/22
Project: Research, Parent

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title = "Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis",

abstract = "Objective To establish whether children born with an orofacial cleft have a higher risk of dental caries than individuals without cleft.Design A systematic review and meta-analysisMethods The search strategy was based on the key words 'cleft lip palate' and 'oral hygiene caries decay'. Ten databases were searched from their inception to April 2016 to identify all relevant studies. All data were extracted by two independent reviewers. The primary outcome measure was caries measured by the decayed, missing, filled surfaces/teeth index (dmfs/dmft or DMFS/DMFT).Results Twenty-four studies met the selection criteria. All of the studies were observational. Twenty-two studies were suitable for inclusion in the meta-analysis. The overall pooled mean difference in dmft was 0.63 (95% CI: 0.47 to 0.79) and in DMFT was 0.28 (95% CI: 0.22 to 0.34).Conclusion Individuals with cleft lip and/or palate have higher caries prevalence, both in the deciduous and the permanent dentitions.",

author = "Viki Worth and Rachel Perry and Anthony Ireland and Andrew Wills and Jonathan Sandy and Ness, {Andrew R}",

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AU - Sandy, Jonathan

AU - Ness, Andrew R

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Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis

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NIHR BRC Nutrition

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