Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

Agnieszka Jazwa; Mateusz Tomczyk; Hevidar M Taha; Elisa Hytonen; Mateusz Stoszko; Lorena Zentilin; Mauro Giacca; Seppo Yla-Herttuala; Costanza Emanueli; Alicja Jozkowicz; Jozef Dulak

doi:10.1186/2045-824X-5-13

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

Agnieszka Jazwa, Mateusz Tomczyk, Hevidar M Taha, Elisa Hytonen, Mateusz Stoszko, Lorena Zentilin, Mauro Giacca, Seppo Yla-Herttuala, Costanza Emanueli, Alicja Jozkowicz, Jozef Dulak

Bristol Medical School (THS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

11 Citations (Scopus)

Abstract

Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth factor-A (VEGF-A, VEGF) and fibroblast growth factor 4 (FGF4) in murine normoperfused and ischemic limb muscles.

Original language	English
Pages (from-to)	13
Journal	Vascular Cell
Volume	5
Issue number	1
DOIs	https://doi.org/10.1186/2045-824X-5-13
Publication status	Published - 1 Jul 2013

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title = "Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia",

abstract = "Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth factor-A (VEGF-A, VEGF) and fibroblast growth factor 4 (FGF4) in murine normoperfused and ischemic limb muscles.",

author = "Agnieszka Jazwa and Mateusz Tomczyk and Taha, {Hevidar M} and Elisa Hytonen and Mateusz Stoszko and Lorena Zentilin and Mauro Giacca and Seppo Yla-Herttuala and Costanza Emanueli and Alicja Jozkowicz and Jozef Dulak",

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TY - JOUR

T1 - Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

AU - Jazwa, Agnieszka

AU - Tomczyk, Mateusz

AU - Taha, Hevidar M

AU - Hytonen, Elisa

AU - Stoszko, Mateusz

AU - Zentilin, Lorena

AU - Giacca, Mauro

AU - Yla-Herttuala, Seppo

AU - Emanueli, Costanza

AU - Jozkowicz, Alicja

AU - Dulak, Jozef

PY - 2013/7/1

Y1 - 2013/7/1

N2 - Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth factor-A (VEGF-A, VEGF) and fibroblast growth factor 4 (FGF4) in murine normoperfused and ischemic limb muscles.

AB - Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth factor-A (VEGF-A, VEGF) and fibroblast growth factor 4 (FGF4) in murine normoperfused and ischemic limb muscles.

U2 - 10.1186/2045-824X-5-13

DO - 10.1186/2045-824X-5-13

M3 - Article (Academic Journal)

C2 - 23816205

VL - 5

SP - 13

JO - Vascular Cell

JF - Vascular Cell

SN - 2045-824X

IS - 1

ER -

Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

Abstract

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