Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia

Agnieszka Jazwa, Mateusz Tomczyk, Hevidar M Taha, Elisa Hytonen, Mateusz Stoszko, Lorena Zentilin, Mauro Giacca, Seppo Yla-Herttuala, Costanza Emanueli, Alicja Jozkowicz, Jozef Dulak

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

Abstract

Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth factor-A (VEGF-A, VEGF) and fibroblast growth factor 4 (FGF4) in murine normoperfused and ischemic limb muscles.
Original languageEnglish
Pages (from-to)13
JournalVascular Cell
Volume5
Issue number1
DOIs
Publication statusPublished - 1 Jul 2013

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    Jazwa, A., Tomczyk, M., Taha, H. M., Hytonen, E., Stoszko, M., Zentilin, L., Giacca, M., Yla-Herttuala, S., Emanueli, C., Jozkowicz, A., & Dulak, J. (2013). Arteriogenic therapy based on simultaneous delivery of VEGF-A and FGF4 genes improves the recovery from acute limb ischemia. Vascular Cell, 5(1), 13. https://doi.org/10.1186/2045-824X-5-13