Assessing IDU prevalence and health consequences (HCV, overdose and drug-related mortality) in a primary care trust: implications for public health action

Matthew Hickman, Vivian Hope, Barbara Coleman, John Parry, Maggie Telfer, John Twigger, Charles Irish, John A A Macleod, Hugh Annett

Research output: Contribution to journalArticle (Academic Journal)peer-review

39 Citations (Scopus)

Abstract

BACKGROUND: We report on an exercise to estimate the prevalence of injecting drug use (IDU) and associated harms in a single primary care trust.

METHODS: Covariate capture-recapture methods to estimate (i) IDU prevalence; respondent driven sampling to measure (ii) prevalence of HCV and HIV and record linkage to measure (iii) mortality risk.

RESULTS: (i) The overall estimated number of IDU was 5540 (95% confidence interval, CI: 4710-6780) for all cases and 3280 (95% CI: 1940-4610) for cases matched to primary care register, i.e. a prevalence of 2.2 and 1.3% aged 15-54, respectively. (ii) The prevalence of HCV, hepatitis B and HIV was: 53, 32 and 0.7%. Over 70% of IDU in Bristol reported having at least one vaccination for HBV; more than half of those who were HCV positive were undiagnosed. (iii) The all-cause and overdose mortality rates for IDU were 0.75 and 0.4% respectively; and the standardized mortality ratio was 7.8 (95% CI: 5.4-10.8).

CONCLUSION: Locally specific and useful intelligence on injecting and its health consequence can be generated to inform local public health action, and may contribute information to validate national prevalence estimates.

Translated title of the contributionAssessing IDU prevalence and health consequences (HCV, overdose and drug-related mortality) in a primary care trust: implications for public health action
Original languageEnglish
Pages (from-to)374-382
Number of pages9
JournalJournal of Public Health (United Kingdom)
Volume31
Issue number3
DOIs
Publication statusPublished - Sep 2009

Bibliographical note

Publisher: Oxford University Press

Keywords

  • Adolescent
  • Adult
  • Age Distribution
  • Cause of Death
  • Cocaine-Related Disorders
  • Confidence Intervals
  • Crack Cocaine
  • Drug Overdose
  • Female
  • Great Britain
  • HIV Infections
  • Hepatitis B
  • Hepatitis C
  • Homeless Persons
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Primary Health Care
  • Public Health
  • Risk Factors
  • Substance Abuse, Intravenous
  • Young Adult

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