TY - JOUR
T1 - Assessing Limb Outcomes in Drug Trials in Peripheral Artery Disease
T2 - The need for a universal and pragmatic definition
AU - Jansen, Shirley
AU - Teraa, Martin
AU - Chan, Noel
AU - Bosch, Jackie
AU - de Borst, Gert Jan
AU - Hinchliffe, Robert J
PY - 2023/9/1
Y1 - 2023/9/1
N2 - To assess the impact of interventions in patients with peripheral arterial disease (PAD), it is important to standardise the definition of limb outcomes for valid comparisons and reliable evidence syntheses. This letter highlights the current variability of outcome definitions in PAD. Moreover, it aims to provide a pragmatic and easily applicable definition of the most essential limb related outcomes with a focus on drug trials.
AB - To assess the impact of interventions in patients with peripheral arterial disease (PAD), it is important to standardise the definition of limb outcomes for valid comparisons and reliable evidence syntheses. This letter highlights the current variability of outcome definitions in PAD. Moreover, it aims to provide a pragmatic and easily applicable definition of the most essential limb related outcomes with a focus on drug trials.
U2 - 10.1016/j.ejvs.2023.06.007
DO - 10.1016/j.ejvs.2023.06.007
M3 - Article (Academic Journal)
C2 - 37327967
SN - 1078-5884
VL - 66
SP - 442
EP - 443
JO - European Journal of Vascular and Endovascular Surgery
JF - European Journal of Vascular and Endovascular Surgery
IS - 3
ER -