Assessing quality of life in patients with colorectal cancer: an update of the EORTC quality of life questionnaire

S Gujral, T Conroy, C Fleissner, O Sezer, PM King, KNL Avery, P Sylvester, M Koller, MAG Sprangers, JM Blazeby, Group on behalf of the European Organisation for Research and Treatment of Cancer Quality of Life

Research output: Contribution to journalArticle (Academic Journal)peer-review

87 Citations (Scopus)

Abstract

The European Organisation for Research and Treatment of Cancer (EORTC) has a portfolio of questionnaire modules to supplement the QLQ-C30 to assess patient reported outcomes in cancer clinical trials. This study updated the module for colorectal cancer. A review of the literature identified 20 articles that used the EORTC colorectal module. Eight papers did not report data from scales addressing sexual function and 8 added additional scales to assess ano-rectal function. Interviews with patients (n = 79) and professionals (n = 11) informed item selection, reduction and modification. A new 29 item module was devised and further patient interviews (n = 120) examined its format and content validity. Patients found the new module acceptable with relevant content. The new module, the EORTC QLQ-CR29, is hypothesised as containing 6 scales and 11 single items. An international study examining its clinical and psychometric validity will be performed.
Translated title of the contributionAssessing quality of life in patients with colorectal cancer: an update of the EORTC quality of life questionnaire
Original languageEnglish
Pages (from-to)1564 - 1573
Number of pages10
JournalEuropean Journal of Cancer
Volume43 (10)
DOIs
Publication statusPublished - Jul 2007

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