Association between CCL2 haplotypes and knee osteoarthritis

S L Hulin-Curtis, J L Bidwell, M J Perry

Research output: Contribution to journalArticle (Academic Journal)peer-review

7 Citations (Scopus)

Abstract

We examined five single nucleotide polymorphisms (SNPs) and reconstructed 5-locus haplotypes of the CCL2 gene, in knee osteoarthritis (OA) cases and in controls. The CCL2 rs2857657 variant (G) allele was observed more frequently in female knee OA cases than in controls. One haplotype (H5) was observed exclusively in the control group (f = 2.3%). Genetic variation in the CCL2 gene may be associated with knee OA.
Original languageEnglish
Pages (from-to)280-3
Number of pages4
JournalInternational Journal of Immunogenetics
Volume40
Issue number4
DOIs
Publication statusPublished - Aug 2013

Bibliographical note

© 2012 John Wiley & Sons Ltd.

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