Association of adult body mass index and height with anxiety, depression, and suicide in the general population: The HUNT Study

O Bjerkeset, P Romundstad, J Evans, DJ Gunnell

Research output: Contribution to journalArticle (Academic Journal)

167 Citations (Scopus)

Abstract

A prospective cohort of 74,332 men and women was used to investigate the association of body mass index and height with suicide, anxiety, and depression. Participants in the Nord-Trøndelag Health Study (Norway, 1984–1986) (HUNT 1) were aged 20 years or more and followed up until December 31, 2002. Anxiety and depression were measured with the Hospital Anxiety and Depression Rating Scale (HADS) in 1995–1997. There were 183 suicides. Suicide risk decreased with increasing body mass index at baseline (1984–1986) in men and women. In models controlling for a range of psychological, social, and lifestyle factors, the hazard ratio per standard deviation increase in body mass index was 0.82 (95% confidence interval: 0.68, 0.98). In contrast, in the subset of participants (n = 44,396) with HADS measures, body mass index at baseline (1984–1986) was positively associated with depression. In fully adjusted models, the odds ratio for depression per standard deviation increase in body mass index (HADS-D: ≥8) was 1.11 (95% confidence interval: 1.07, 1.15). In fully adjusted models, there was no association of height with the incidence of suicide or depression. Raised body mass index is associated with an increased risk of depression but reduced risk of suicide in men and women. The mechanisms underlying these different associations require clarification.
Translated title of the contributionAssociation of adult body mass index and height with anxiety, depression, and suicide in the general population: the Hunt Study
Original languageEnglish
Pages (from-to)193 - 202
Number of pages10
JournalAmerican Journal of Epidemiology
Volume167
Issue number2
DOIs
Publication statusPublished - Jan 2008

Bibliographical note

Publisher: Oxford University Press

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