Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

Adam Barker; Stephen J Sharp; Nicholas J Timpson; Nabila Bouatia-Naji; Nicole M Warrington; Stavroula Kanoni; Lawrence J Beilin; Soren Brage; Panos Deloukas; David M Evans; Anders Grontved; Neelam Hassanali; Deborah A Lawlor; Cecile Lecoeur; Ruth J F Loos; Stephen J Lye; Mark I McCarthy; Trevor A Mori; Ndeye Coumba Ndiaye; John P Newnham; Ioanna Ntalla; Craig E Pennell; Beate St Pourcain; Inga Prokopenko; Susan M Ring; Naveed Sattar; Sophie Visvikis-Siest; George V Dedoussis; Lyle J Palmer; Philippe Froguel; George Davey Smith; Ulf Ekelund; Nicholas J Wareham; Claudia Langenberg

doi:10.2337/db10-1575

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

Adam Barker, Stephen J Sharp, Nicholas J Timpson, Nabila Bouatia-Naji, Nicole M Warrington, Stavroula Kanoni, Lawrence J Beilin, Soren Brage, Panos Deloukas, David M Evans, Anders Grontved, Neelam Hassanali, Deborah A Lawlor, Cecile Lecoeur, Ruth J F Loos, Stephen J Lye, Mark I McCarthy, Trevor A Mori, Ndeye Coumba Ndiaye, John P NewnhamIoanna Ntalla, Craig E Pennell, Beate St Pourcain, Inga Prokopenko, Susan M Ring, Naveed Sattar, Sophie Visvikis-Siest, George V Dedoussis, Lyle J Palmer, Philippe Froguel, George Davey Smith, Ulf Ekelund, Nicholas J Wareham, Claudia Langenberg

Research output: Contribution to journal › Article (Academic Journal) › peer-review

102 Citations (Scopus)

Abstract

To investigate whether associations of common genetic variants recently identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy children and adolescents.

Original language	English
Pages (from-to)	1805-12
Number of pages	8
Journal	Diabetic Medicine
Volume	60
Issue number	6
DOIs	https://doi.org/10.2337/db10-1575
Publication status	Published - 2011

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Barker, A., Sharp, S. J., Timpson, N. J., Bouatia-Naji, N., Warrington, N. M., Kanoni, S., Beilin, L. J., Brage, S., Deloukas, P., Evans, D. M., Grontved, A., Hassanali, N., Lawlor, D. A., Lecoeur, C., Loos, R. J. F., Lye, S. J., McCarthy, M. I., Mori, T. A., Ndiaye, N. C., ... Langenberg, C. (2011). Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children. Diabetic Medicine, 60(6), 1805-12. https://doi.org/10.2337/db10-1575

@article{d706b460405d4b888815540055412ed1,

title = "Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children",

abstract = "To investigate whether associations of common genetic variants recently identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy children and adolescents.",

author = "Adam Barker and Sharp, \{Stephen J\} and Timpson, \{Nicholas J\} and Nabila Bouatia-Naji and Warrington, \{Nicole M\} and Stavroula Kanoni and Beilin, \{Lawrence J\} and Soren Brage and Panos Deloukas and Evans, \{David M\} and Anders Grontved and Neelam Hassanali and Lawlor, \{Deborah A\} and Cecile Lecoeur and Loos, \{Ruth J F\} and Lye, \{Stephen J\} and McCarthy, \{Mark I\} and Mori, \{Trevor A\} and Ndiaye, \{Ndeye Coumba\} and Newnham, \{John P\} and Ioanna Ntalla and Pennell, \{Craig E\} and \{St Pourcain\}, Beate and Inga Prokopenko and Ring, \{Susan M\} and Naveed Sattar and Sophie Visvikis-Siest and Dedoussis, \{George V\} and Palmer, \{Lyle J\} and Philippe Froguel and Smith, \{George Davey\} and Ulf Ekelund and Wareham, \{Nicholas J\} and Claudia Langenberg",

year = "2011",

doi = "10.2337/db10-1575",

language = "English",

volume = "60",

pages = "1805--12",

journal = "Diabetic Medicine",

issn = "1464-5491",

publisher = "Wiley-Blackwell",

number = "6",

}

Barker, A, Sharp, SJ, Timpson, NJ, Bouatia-Naji, N, Warrington, NM, Kanoni, S, Beilin, LJ, Brage, S, Deloukas, P, Evans, DM, Grontved, A, Hassanali, N, Lawlor, DA, Lecoeur, C, Loos, RJF, Lye, SJ, McCarthy, MI, Mori, TA, Ndiaye, NC, Newnham, JP, Ntalla, I, Pennell, CE, St Pourcain, B, Prokopenko, I, Ring, SM, Sattar, N, Visvikis-Siest, S, Dedoussis, GV, Palmer, LJ, Froguel, P, Smith, GD, Ekelund, U, Wareham, NJ & Langenberg, C 2011, 'Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children', Diabetic Medicine, vol. 60, no. 6, pp. 1805-12. https://doi.org/10.2337/db10-1575

TY - JOUR

T1 - Association of genetic Loci with glucose levels in childhood and adolescence

T2 - a meta-analysis of over 6,000 children

AU - Barker, Adam

AU - Sharp, Stephen J

AU - Timpson, Nicholas J

AU - Bouatia-Naji, Nabila

AU - Warrington, Nicole M

AU - Kanoni, Stavroula

AU - Beilin, Lawrence J

AU - Brage, Soren

AU - Deloukas, Panos

AU - Evans, David M

AU - Grontved, Anders

AU - Hassanali, Neelam

AU - Lawlor, Deborah A

AU - Lecoeur, Cecile

AU - Loos, Ruth J F

AU - Lye, Stephen J

AU - McCarthy, Mark I

AU - Mori, Trevor A

AU - Ndiaye, Ndeye Coumba

AU - Newnham, John P

AU - Ntalla, Ioanna

AU - Pennell, Craig E

AU - St Pourcain, Beate

AU - Prokopenko, Inga

AU - Ring, Susan M

AU - Sattar, Naveed

AU - Visvikis-Siest, Sophie

AU - Dedoussis, George V

AU - Palmer, Lyle J

AU - Froguel, Philippe

AU - Smith, George Davey

AU - Ekelund, Ulf

AU - Wareham, Nicholas J

AU - Langenberg, Claudia

PY - 2011

Y1 - 2011

N2 - To investigate whether associations of common genetic variants recently identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy children and adolescents.

AB - To investigate whether associations of common genetic variants recently identified for fasting glucose or insulin levels in nondiabetic adults are detectable in healthy children and adolescents.

U2 - 10.2337/db10-1575

DO - 10.2337/db10-1575

M3 - Article (Academic Journal)

C2 - 21515849

SN - 1464-5491

VL - 60

SP - 1805

EP - 1812

JO - Diabetic Medicine

JF - Diabetic Medicine

IS - 6

ER -

Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children

Abstract

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