Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes

Lisa M Maier; Joanna M M Howson; Neil Walker; Gavin P Spickett; Richard W Jones; Susan M Ring; Wendy L McArdle; Christopher E Lowe; Rebecca Bailey; Felicity Payne; John A Todd; David P Strachan

doi:10.1016/j.jaci.2005.12.1354

Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes

Lisa M Maier, Joanna M M Howson, Neil Walker, Gavin P Spickett, Richard W Jones, Susan M Ring, Wendy L McArdle, Christopher E Lowe, Rebecca Bailey, Felicity Payne, John A Todd, David P Strachan

Bristol Medical School (PHS)

Research output: Contribution to journal › Article (Academic Journal) › peer-review

63 Citations (Scopus)

Abstract

Atopic illnesses, related to high circulating IgE levels, and the autoimmune disease type 1 diabetes, have been reported to be inversely associated. One possible explanation is that susceptibility alleles for one disease provide protection for the other.

Original language	English
Pages (from-to)	1306-13
Number of pages	8
Journal	Journal of Allergy and Clinical Immunology
Volume	117
Issue number	6
DOIs	https://doi.org/10.1016/j.jaci.2005.12.1354
Publication status	Published - 2006

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Maier, L. M., Howson, J. M. M., Walker, N., Spickett, G. P., Jones, R. W., Ring, S. M., McArdle, W. L., Lowe, C. E., Bailey, R., Payne, F., Todd, J. A., & Strachan, D. P. (2006). Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes. Journal of Allergy and Clinical Immunology, 117(6), 1306-13. https://doi.org/10.1016/j.jaci.2005.12.1354

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abstract = "Atopic illnesses, related to high circulating IgE levels, and the autoimmune disease type 1 diabetes, have been reported to be inversely associated. One possible explanation is that susceptibility alleles for one disease provide protection for the other.",

author = "Maier, {Lisa M} and Howson, {Joanna M M} and Neil Walker and Spickett, {Gavin P} and Jones, {Richard W} and Ring, {Susan M} and McArdle, {Wendy L} and Lowe, {Christopher E} and Rebecca Bailey and Felicity Payne and Todd, {John A} and Strachan, {David P}",

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T2 - evidence against an inverse association of atopy and diabetes

AU - Maier, Lisa M

AU - Howson, Joanna M M

AU - Walker, Neil

AU - Spickett, Gavin P

AU - Jones, Richard W

AU - Ring, Susan M

AU - McArdle, Wendy L

AU - Lowe, Christopher E

AU - Bailey, Rebecca

AU - Payne, Felicity

AU - Todd, John A

AU - Strachan, David P

PY - 2006

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N2 - Atopic illnesses, related to high circulating IgE levels, and the autoimmune disease type 1 diabetes, have been reported to be inversely associated. One possible explanation is that susceptibility alleles for one disease provide protection for the other.

AB - Atopic illnesses, related to high circulating IgE levels, and the autoimmune disease type 1 diabetes, have been reported to be inversely associated. One possible explanation is that susceptibility alleles for one disease provide protection for the other.

U2 - 10.1016/j.jaci.2005.12.1354

DO - 10.1016/j.jaci.2005.12.1354

M3 - Article (Academic Journal)

C2 - 16750991

SN - 0091-6749

VL - 117

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EP - 1313

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

IS - 6

ER -

Association of IL13 with total IgE: evidence against an inverse association of atopy and diabetes

Abstract

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