Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias

MR Munafo; IJ Matheson; J Flint

Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias

MR Munafo, IJ Matheson, J Flint

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Abstract

We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Potential publication bias represents a genuine risk to the integrity of published research, but its impact has rarely been documented. We observed a small effect of the DRD2 Taq1A polymorphism on risk of alcoholism, indicating increased alcoholism in individuals possessing the A1 allele of the Taq1A polymorphism (OR=1.21, 95% CI 1.13–1.30, P

Translated title of the contribution	Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias
Original language	English
Pages (from-to)	454 - 461
Number of pages	8
Journal	Molecular Psychiatry
Volume	12
Publication status	Published - 2009

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@article{47c5ecdec7434f429a15eeacd4041281,

title = "Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias",

abstract = "We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Potential publication bias represents a genuine risk to the integrity of published research, but its impact has rarely been documented. We observed a small effect of the DRD2 Taq1A polymorphism on risk of alcoholism, indicating increased alcoholism in individuals possessing the A1 allele of the Taq1A polymorphism (OR=1.21, 95% CI 1.13–1.30, P",

author = "MR Munafo and IJ Matheson and J Flint",

year = "2009",

language = "English",

volume = "12",

pages = "454 -- 461",

journal = "Molecular Psychiatry",

issn = "1476-5578",

publisher = "Springer Nature",

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TY - JOUR

T1 - Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias

AU - Munafo, MR

AU - Matheson, IJ

AU - Flint, J

PY - 2009

Y1 - 2009

N2 - We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Potential publication bias represents a genuine risk to the integrity of published research, but its impact has rarely been documented. We observed a small effect of the DRD2 Taq1A polymorphism on risk of alcoholism, indicating increased alcoholism in individuals possessing the A1 allele of the Taq1A polymorphism (OR=1.21, 95% CI 1.13–1.30, P

AB - We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Potential publication bias represents a genuine risk to the integrity of published research, but its impact has rarely been documented. We observed a small effect of the DRD2 Taq1A polymorphism on risk of alcoholism, indicating increased alcoholism in individuals possessing the A1 allele of the Taq1A polymorphism (OR=1.21, 95% CI 1.13–1.30, P

M3 - Article (Academic Journal)

SN - 1476-5578

VL - 12

SP - 454

EP - 461

JO - Molecular Psychiatry

JF - Molecular Psychiatry

ER -

Association of the DRD2 Taq1 polymorphism and alcoholism: A meta-analysis of case-control studies and evidence of publication bias

Abstract

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