Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children

Diana L Dos Santos Ferreira, Abigail Fraser, Laura D Howe, Siana Jones, George Davey Smith, Debbie A Lawlor, Robyn Tapp, Andy R Ness, John E Deanfield, N Chaturvedi, A Hughes

Research output: Contribution to journalArticle (Academic Journal)peer-review

2 Citations (Scopus)
240 Downloads (Pure)

Abstract

Most studies relating blood pressure (BP) to target organ damage measure BP at the brachial artery, but pulse pressure (PP) and systolic BP (SBP) in the aorta are lower than the corresponding peripheral measures. In adults, aortic (central) PP and SBP have been shown to be more closely related to target organ damage and cardiovascular events than peripheral pressures. We compared central and peripheral PP and their associations with concurrent measures of cardiac structure and function in a large, population-based cohort of adolescents.
Original languageEnglish
Pages (from-to)2048-2050
Number of pages3
JournalJournal of the American College of Cardiology
Volume65
Issue number18
Early online date12 May 2015
DOIs
Publication statusPublished - May 2015

Keywords

  • brachial blood pressure
  • central blood pressure
  • cardiovascular disease risk factors
  • systolic function
  • diastolic function
  • heart structure
  • adolescents
  • ALSPAC

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