Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children

Diana L Dos Santos Ferreira; Abigail Fraser; Laura D Howe; Siana Jones; George Davey Smith; Debbie A Lawlor; Robyn Tapp; Andy R Ness; John E Deanfield; N Chaturvedi; A Hughes

doi:10.1016/j.jacc.2015.01.060

Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children

Diana L Dos Santos Ferreira, Abigail Fraser, Laura D Howe, Siana Jones, George Davey Smith, Debbie A Lawlor, Robyn Tapp, Andy R Ness, John E Deanfield, N Chaturvedi, A Hughes

Research output: Contribution to journal › Article (Academic Journal) › peer-review

5 Citations (Scopus)

308 Downloads (Pure)

Abstract

Most studies relating blood pressure (BP) to target organ damage measure BP at the brachial artery, but pulse pressure (PP) and systolic BP (SBP) in the aorta are lower than the corresponding peripheral measures. In adults, aortic (central) PP and SBP have been shown to be more closely related to target organ damage and cardiovascular events than peripheral pressures. We compared central and peripheral PP and their associations with concurrent measures of cardiac structure and function in a large, population-based cohort of adolescents.

Original language	English
Pages (from-to)	2048-2050
Number of pages	3
Journal	Journal of the American College of Cardiology
Volume	65
Issue number	18
Early online date	12 May 2015
DOIs	https://doi.org/10.1016/j.jacc.2015.01.060
Publication status	Published - May 2015

Keywords

brachial blood pressure
central blood pressure
cardiovascular disease risk factors
systolic function
diastolic function
heart structure
adolescents
ALSPAC

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jacc.2015.01.060

BP_cardiacfunct_JACC_R1_1512Accepted author manuscript, 356 KB

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Lifecourse epidemiology of female reproductive health and its relation to chronic disease
Fraser, A. (Principal Investigator)
1/12/14 → 20/02/20
Project: Research
MRC UoB UNITE Unit - Programme 5
Lawlor, D. A. (Principal Investigator) & Lawlor, D. A. (Principal Investigator)
1/06/13 → 31/03/18
Project: Research

Professor Abigail Fraser
- Abigail.Fraserbristol.acuk
- Bristol Medical School (PHS) - Professor of Epidemiology
- Bristol Poverty Institute
- Bristol Population Health Science Institute
- MRC Integrative Epidemiology Unit
- Centre for Academic Primary Care
Person: Academic , Member

Cite this

Dos Santos Ferreira, D. L., Fraser, A., Howe, L. D., Jones, S., Davey Smith, G., Lawlor, D. A., Tapp, R., Ness, A. R., Deanfield, J. E., Chaturvedi, N., & Hughes, A. (2015). Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children. Journal of the American College of Cardiology, 65(18), 2048-2050. https://doi.org/10.1016/j.jacc.2015.01.060

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title = "Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children",

abstract = "Most studies relating blood pressure (BP) to target organ damage measure BP at the brachial artery, but pulse pressure (PP) and systolic BP (SBP) in the aorta are lower than the corresponding peripheral measures. In adults, aortic (central) PP and SBP have been shown to be more closely related to target organ damage and cardiovascular events than peripheral pressures. We compared central and peripheral PP and their associations with concurrent measures of cardiac structure and function in a large, population-based cohort of adolescents.",

keywords = "brachial blood pressure, central blood pressure, cardiovascular disease risk factors, systolic function, diastolic function, heart structure, adolescents, ALSPAC",

author = "\{Dos Santos Ferreira\}, \{Diana L\} and Abigail Fraser and Howe, \{Laura D\} and Siana Jones and \{Davey Smith\}, George and Lawlor, \{Debbie A\} and Robyn Tapp and Ness, \{Andy R\} and Deanfield, \{John E\} and N Chaturvedi and A Hughes",

year = "2015",

month = may,

doi = "10.1016/j.jacc.2015.01.060",

language = "English",

volume = "65",

pages = "2048--2050",

journal = "Journal of the American College of Cardiology",

issn = "0735-1097",

publisher = "Elsevier Inc.",

number = "18",

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Dos Santos Ferreira, DL, Fraser, A , Howe, LD, Jones, S, Davey Smith, G , Lawlor, DA, Tapp, R, Ness, AR, Deanfield, JE, Chaturvedi, N & Hughes, A 2015, 'Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children', Journal of the American College of Cardiology, vol. 65, no. 18, pp. 2048-2050. https://doi.org/10.1016/j.jacc.2015.01.060

Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children. / Dos Santos Ferreira, Diana L; Fraser, Abigail ; Howe, Laura D et al.
In: Journal of the American College of Cardiology, Vol. 65, No. 18, 05.2015, p. 2048-2050.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

TY - JOUR

T1 - Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort

T2 - the Avon Longitudinal Study of Parents and Children

AU - Dos Santos Ferreira, Diana L

AU - Fraser, Abigail

AU - Howe, Laura D

AU - Jones, Siana

AU - Davey Smith, George

AU - Lawlor, Debbie A

AU - Tapp, Robyn

AU - Ness, Andy R

AU - Deanfield, John E

AU - Chaturvedi, N

AU - Hughes, A

PY - 2015/5

Y1 - 2015/5

N2 - Most studies relating blood pressure (BP) to target organ damage measure BP at the brachial artery, but pulse pressure (PP) and systolic BP (SBP) in the aorta are lower than the corresponding peripheral measures. In adults, aortic (central) PP and SBP have been shown to be more closely related to target organ damage and cardiovascular events than peripheral pressures. We compared central and peripheral PP and their associations with concurrent measures of cardiac structure and function in a large, population-based cohort of adolescents.

AB - Most studies relating blood pressure (BP) to target organ damage measure BP at the brachial artery, but pulse pressure (PP) and systolic BP (SBP) in the aorta are lower than the corresponding peripheral measures. In adults, aortic (central) PP and SBP have been shown to be more closely related to target organ damage and cardiovascular events than peripheral pressures. We compared central and peripheral PP and their associations with concurrent measures of cardiac structure and function in a large, population-based cohort of adolescents.

KW - brachial blood pressure

KW - central blood pressure

KW - cardiovascular disease risk factors

KW - systolic function

KW - diastolic function

KW - heart structure

KW - adolescents

KW - ALSPAC

U2 - 10.1016/j.jacc.2015.01.060

DO - 10.1016/j.jacc.2015.01.060

M3 - Article (Academic Journal)

C2 - 25953754

SN - 0735-1097

VL - 65

SP - 2048

EP - 2050

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

IS - 18

ER -

Dos Santos Ferreira DL, Fraser A , Howe LD, Jones S, Davey Smith G , Lawlor DA et al. Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children. Journal of the American College of Cardiology. 2015 May;65(18):2048-2050. Epub 2015 May 12. doi: 10.1016/j.jacc.2015.01.060

Associations of central and peripheral blood pressure with cardiac structure and function in an adolescent birth cohort: the Avon Longitudinal Study of Parents and Children

Abstract

Keywords

UN SDGs

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Projects

Lifecourse epidemiology of female reproductive health and its relation to chronic disease

MRC UoB UNITE Unit - Programme 5

Profiles

Professor Abigail Fraser

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