Asymmetric deprotonation and dearomatising cyclisation of N-benzyl benzamides using chiral lithium amides: Formal synthesis of (-)-kainic acid

Jonathan Clayden*, Christel J. Menet, Darren J. Mansfield

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

56 Citations (Scopus)

Abstract

Chiral lithium amides deprotonate N-benzyl benzamides enantioselectively, initiating an asymmetric dearomatising cyclisation to enantiomerically enriched isoindolinones.

Original languageEnglish
Pages (from-to)38-39
Number of pages2
JournalChemical Communications
Issue number1
Early online date3 Dec 2001
DOIs
Publication statusPublished - 7 Jan 2002

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