Abstract
Sulfur ylide methodology has been used to construct the Taxol side chain with a high degree of enantioselectivity via a trans-aziridine followed by stereospecific rearrangement of the trans-benzoylaziridine into a trans-oxazoline.
| Original language | English |
|---|---|
| Pages (from-to) | 3987-3990 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 5 |
| Issue number | 21 |
| DOIs | |
| Publication status | Published - 16 Oct 2003 |
Research Groups and Themes
- Organic & Biological
Keywords
- VIC-AMINO ALCOHOLS
- IN-SITU GENERATION
- ENANTIOSELECTIVE SYNTHESIS
- CHIRAL AZIRIDINES
- IMINES
- EPOXIDATION
- ROUTE
- CYCLOPROPANATION
- REGIODIVERGENT
- REARRANGEMENT
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