Abstract
Enantiomerically pure tertiary thiols provide a major synthetic challenge, and despite the importance of chiral sulfur-containing compounds in biological and medicinal chemistry, surprisingly few effective methods are suitable for the asymmetric synthesis of tertiary thiols. This review details the most practical of the methods available.
Original language | English |
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Article number | A68 |
Pages (from-to) | 582-595 |
Number of pages | 14 |
Journal | Beilstein Journal of Organic Chemistry |
Volume | 7 |
DOIs | |
Publication status | Published - 10 May 2011 |
Keywords
- Asymmetric synthesis
- Organolithium
- Substitution
- Sulfur
- Thiol