Abstract
Enantiomerically pure tertiary thiols provide a major synthetic challenge, and despite the importance of chiral sulfur-containing compounds in biological and medicinal chemistry, surprisingly few effective methods are suitable for the asymmetric synthesis of tertiary thiols. This review details the most practical of the methods available.
| Original language | English |
|---|---|
| Article number | A68 |
| Pages (from-to) | 582-595 |
| Number of pages | 14 |
| Journal | Beilstein Journal of Organic Chemistry |
| Volume | 7 |
| DOIs | |
| Publication status | Published - 10 May 2011 |
Keywords
- Asymmetric synthesis
- Organolithium
- Substitution
- Sulfur
- Thiol