Atropisomers and near-atropisomers: achieving stereoselectivity by exploiting the conformational preferences of aromatic amides

Jonathan Clayden*

*Corresponding author for this work

Research output: Contribution to journalArticle (Academic Journal)peer-review

92 Citations (Scopus)

Abstract

The conformational preferences of aromatic amides are remarkably easy to control with a high degree of selectivity. This article reviews the consequences of this unusual form of stereocontrol, which enables for example the asymmetric synthesis of atropisomers and the ability to achieve remote stereocontrol by conformational relay.

Original languageEnglish
Pages (from-to)127-135
Number of pages9
JournalChemical Communications
Issue number2
Early online date14 Oct 2003
DOIs
Publication statusPublished - 21 Jan 2004

Fingerprint Dive into the research topics of 'Atropisomers and near-atropisomers: achieving stereoselectivity by exploiting the conformational preferences of aromatic amides'. Together they form a unique fingerprint.

Cite this